英语翻译A certificate from the shipping company or their agent stating that the goods are shipping on APL,MAERSK,CMA CGM,CHINA SHIPPING,COSCO,OOCL,HYUNDAI,NYK,UASC,EMIRATES SHIPPING,K LINE,PIL,EVERGREEN,WANHAI LINE VESSELS ONLY:1) That are exempted from the "SOLAS" convention certification requirement and is not required to have a certificate of conformity to the ISM code or that have a current ISM code certificate,if the carrying vessel is subject to "SOLAS".2) Covered by the institute classification clause.2) That are allowed by the Arab authorities to call at Arabian ports an not schedule to call at any israel port during its voyage to the U.A.E..
从船公司或他们的代理人证明,证明货物是杀伤人员地雷,马士基,达飞轮船,中国海运,中远,东方海外,韩国现代,日本邮船,UASC,阿联酋航运,K线,太平船务,长荣,万海航运线路船只只：1）,这些获豁免的“海上人命安全公约”公约认证要求,也不需要有一个合格证书ISM规则,或具有当前国际安全管理代码证书,如果承运船只受到“海上人命安全公约”.2）所涵盖的机构分类条款.2）被允许由阿拉伯当局在阿拉伯港口停靠的一不计划在任何以色列港口停靠在其航行到阿联酋.
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证书,船公司或其代理机构说明货物泛舟轮船,马士基、CMA CGM、中国船舶,中远,东方海外、现代、NYK,UASC、阿联酋航运、K线,公益诉讼,常绿,万海线只船舶。
1)免徵 "国际海上人员安全公约”会议的认证要求,则不要求有符合证书是否是ISM规则或当前国际安全管理规则的代码证书,如果该船不受 "国际海上人员安全公约”。
2)涵盖了学院船级条款。
2)阿拉伯当局所允许的,可以停泊在阿拉伯港...
一份船公司或他们的代理人证明，证明货物是只由APL，马士基，达飞轮船，中国海运，中远，东方海外，韩国现代，日本邮船，UASC，阿联酋航运，K线，太平船务，长荣，万海航运线路船只运输： 1）这些获豁免的“海上人命安全公约”公约认证要求，如果承运船只受到“海上人命安全公约”，就不需要有一个ISM规则合格证书，或具有当前国际安全管理代码证书。2）所涵盖的机构分类条款。 2）...
从的运输公司或阐明他们的代理，物品在APL， MAERSK， CMA CGM运输，中国运输， COSCO， OOCL， HYUNDAI， NYK， UASC，只运输的酋长管辖区， K线， PIL，常青树， WANHAI线船的一份证明：从“SOLAS”大会证明要求被豁免和没有要求有合格证明到主义代码或有一份当前主义代码证明的1)，如果运载的船是受“SOLAS支配”。2)包括由学院船级条款。...
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The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged.
Please click on the link to the left to view the PIL in PDF format.
Text only version for the visually impairedBelow is a text only representation of the Patient Information leaflet. The original may contain images or tables and can be viewed in PDF format using the link to the left. This PIL may be available from the RNIB in large print, Braille or audio CD. For further information please call the RNIB Medicine Leaflet line on 0. The product code(s) for this leaflet is/are: PL.
Due to regulatory changes, the content of the following Patient Information Leaflet may vary from the one found in your medicine pack. Please compare the 'Leaflet prepared/revised date' towards the end of the leaflet to establish if there have been any changes.
If you have any doubts or queries about your medication, please contact your doctor or pharmacist.
Microgynon(R) 30
Levonorgestrel
Ethinylestradiol
They are one of the most reliable reversible methods of contraception if used correctly.
They slightly increase the risk of having a blood clot in the veins and arteries, especially in the first year or when restarting a combined hormonal contraceptive following a break of 4 or more weeks.
Please be alert and see your doctor if you think you may have symptoms of a blood clot (see section 2.3 ‘Blood clots’).
The Pill may reduce your risk of cancer of the ovary and womb if used in the long term.
The Pill will not protect you against sexually transmitted diseases.
This medicine can increase your risk of problems such as blood clots and breast cancer.
Some women should not take the Pill because of current medical problems or illnesses. Please read this leaflet to make sure Microgynon 30 is right for you.
To prevent pregnancy it is important to take Microgynon 30 as instructed and start each pack on time. Please make sure that you understand what to do if you miss a pill or if you think you are pregnant.
Keep this leaflet. You may need to read it again.
If you have any questions or need more advice, ask your doctor, family planning nurse or pharmacist.
This medicine has been prescribed for you. Do not pass it on to others. It may harm them.
If any of the side effects gets severe, or if you notice any not listed in this leaflet, please tell your doctor, family planning nurse or pharmacist.
1 What Microgynon 30 does
2 What you need to know before you use Microgynon 30
3 Taking Microgynon 30
3.3 A missed pill
4 Possible side effects
5 How to store Microgynon 30
6 What is in Microgynon 30 and who makes it
Microgynon 30 is a combined oral contraceptive pill (‘the Pill’). You take it to stop you getting pregnant.
This contraceptive contains two types of female sex hormones, oestrogen and progestogen. These hormones stop you getting pregnant by working in three ways: by preventing an egg being releas by making the fluid (mucus) in your cervix thicker, which makes it more difficult for spe and by preventing the lining of your womb thickening enough for an egg to grow in it.
Microgynon 30 is a 21-day Pill – you take one each day for 21 days, followed by 7 days when you take no pills.
The benefits of taking the Pill include:
it is one of the most reliable reversible methods of contraception if used correctly
it doesn’t interrupt sex
it usually makes your periods regular, lighter and less painful
it may help with pre-menstrual symptoms.
Microgynon 30 will not protect you against sexually transmitted infections, such as Chlamydia or HIV. Only condoms can help to do this.
Microgynon 30 needs to be taken as directed to prevent pregnancy.
Before you start using Microgynon 30 you should read the information on blood clots in section 2. It is particularly important to read the symptoms of a blood clot – see Section 2.3 ‘Blood clots’.
It’s important that you understand the benefits and risks of taking the Pill before you start taking it, or when deciding whether to carry on taking it. Although the Pill is suitable for most healthy women it isn’t suitable for everyone.
Tell your doctor if you have any of the illnesses or risk factors mentioned in this leaflet.
Your doctor will ask about you and your family’s medical problems, check your blood pressure and exclude the likelihood of you being pregnant. You may also need other checks, such as a breast examination, but only if these examinations are necessary for you, or if you have any special concerns.
You will need regular check-ups with your doctor or family planning nurse, usually when you need another prescription of the Pill.
You should go for regular cervical smear tests.
Check your breasts and nipples every month for changes – tell your doctor if you can see or feel anything odd, such as lumps or dimpling of the skin.
If you need a blood test tell your doctor that you are taking the Pill, because the Pill can affect the results of some tests.
If you’re going to have an operation, make sure your doctor knows about it. You may need to stop taking the Pill about 4–6 weeks before the operation. This is to reduce the risk of a blood clot (see section 2.3). Your doctor will tell you when you can start taking the Pill again.
You should not use Microgynon 30 if you have any of the conditions listed below. If you do have any of the conditions listed below, you must tell your doctor. Your doctor will discuss with you what other form of birth control would be more appropriate.
Do not take Microgynon 30:
If you have (or have ever had) a blood clot in a blood vessel of your legs (deep vein thrombosis, DVT), your lungs (pulmonary embolus, PE) or other organs
If you know you have a disorder affecting your blood clotting – for instance, protein C deficiency, protein S deficiency, antithrombin-III deficiency, Factor V Leiden or antiphospholipid antibodies
If you need an operation or if you are off your feet for a long time (see section ‘Blood clots’)
If you have ever had a heart attack or stroke
If you have (or have ever had) angina pectoris (a condition that causes severe chest pain and may be a first sign of a heart attack) or transient ischaemic attack (TIA – temporary stroke symptoms)
If you have any of the following diseases that may increase your risk of a clot in the arteries:
severe diabetes with blood vessel damage
very high blood pressure
a very high level of fat in the blood (cholesterol or triglycerides)
a condition known as hyperhomocysteinaemia
If you have (or have ever had) a type of migraine called ‘migraine with aura’
If you have or have ever had breast cancer
If you have ever had a severe liver disease, and you have been told by your doctor that your liver function test results are not yet back to normal
If you have ever had liver tumours
If you are allergic (hypersensitive) to any of the ingredients in Microgynon 30.
Tell your doctor or family planning nurse if you have any medical problems or illnesses.
When should you contact your doctor?
Seek urgent medical attention
if you notice possible signs of a blood clot that may mean you are suffering from a blood clot in the leg (i.e. deep vein thrombosis), a blood clot in the lung (i.e. pulmonary embolism), a heart attack or a stroke (see 'Blood clots' section below).
For a description of the symptoms of these serious side effects please go to “How to recognise a blood clot”.
Some of the conditions listed below can be made worse by taking the Pill. Or they may mean it is less suitable for you. You may still be able to take Microgynon 30 but you need to take special care and have check-ups more often.
Tell your doctor if any of the following conditions apply to you.
If the condition develops, or gets worse while you are using Microgynon 30, you should also tell your doctor.
If you have Crohn’s disease or ulcerative colitis (chronic inflammatory bowel disease)
If you have systemic lupus erythematosus (SLE – a disease affecting your natural defence system)
If you have haemolytic uraemic syndrome (HUS – a disorder of blood clotting causing failure of the kidneys)
If you have sickle cell anaemia (an inherited disease of the red blood cells)
If you have inflammation of the pancreas (pancreatitis)
If you have elevated levels of fat in the blood (hypertriglyceridaemia) or a positive family history for this condition. Hypertriglyceridaemia has been associated with an increased risk of developing pancreatitis (inflammation of the pancreas)
If you need an operation, or you are off your feet for a long time (see in section 2 ‘Blood clots’)
If you have just given birth you are at an increased risk of blood clots. You should ask your doctor how soon after delivery you can start taking Microgynon 30
If you have an inflammation in the veins under the skin (superficial thrombophlebitis)
If you have varicose veins
If you have diabetes
If you or your close family have ever had problems with your heart, or circulation such as high blood pressure
If you or your close family have ever had problems with blood clotting
If you have the inherited disease called porphyria
If you are overweight (obese)
If you have migraines
If you have any illness that worsened during pregnancy or previous use of the Pill (see section 4.2)
Using a combined hormonal contraceptive such as Microgynon 30 increases your risk of developing a blood clot compared with not using one. In rare cases a blood clot can block vessels and cause serious problems.
Blood clots can develop:
in veins (referred to as a ‘venous thrombosis’, ‘venous thromboembolism’ or VTE);
in the arteries (referred to as an ‘arterial thrombosis’, ‘arterial thromboembolism’ or ATE).
Recovery from blood clots is not always complete. Rarely, there may be serious lasting effects or, very rarely, they may be fatal.
It is important to remember that the overall risk of having a harmful blood clot due to Microgynon 30 is small.
HOW TO RECOGNISE A BLOOD CLOT
Seek urgent medical attention if you notice any of the following signs or symptoms.
Are you experiencing any of these signs?
swelling of one leg or along a vein in the leg or foot especially when accompanied by:
pain or tenderness in the leg which may be felt only when standing or walking
increased warmth in the affected leg
change in colour of the skin on the leg e.g. turning pale, red or blue
What are you possibly suffering from?
Deep vein thrombosis
Are you experiencing any of these signs?
sudden unexplained breathlessness or rapid breathing
sudden cough without an obvious cause, which may bring up blood
sharp chest pain which may increase with deep breathing
severe light headedness or dizziness
rapid or irregular heartbeat
severe pain in your stomach
If you are unsure, talk to a doctor as some of these symptoms such as coughing or being short of breath may be mistaken for a milder condition such as a respiratory tract infection (e.g. a ‘common cold’).
What are you possibly suffering from?
Pulmonary embolism
Are you experiencing any of these signs?
Symptoms most commonly occur in one eye:
immediate loss of vision or
painless blurring of vision which can progress to loss of vision
What are you possibly suffering from?
Retinal vein thrombosis (blood clot in the eye)
Are you experiencing any of these signs?
chest pain, discomfort, pressure, heaviness
sensation of squeezing or fullness in the chest, arm or below the breastbone
fullness, indigestion or choking feeling
upper body discomfort radiating to the back, jaw, throat, arm and stomach
sweating, nausea, vomiting or dizziness
extreme weakness, anxiety, or shortness of breath
rapid or irregular heartbeats
What are you possibly suffering from?
Heart attack
Are you experiencing any of these signs?
sudden weakness or numbness of the face, arm or leg, especially on one side of the body
sudden confusion, trouble speaking or understanding
sudden trouble seeing in one or both eyes
sudden trouble walking, dizziness, loss of balance or coordination
sudden, severe or prolonged headache with no known cause
loss of consciousness or fainting with or without seizure
Sometimes the symptoms of stroke can be brief with an almost immediate and full recovery, but you should still seek urgent medical attention as you may be at risk of another stroke.
What are you possibly suffering from?
Are you experiencing any of these signs?
swelling and slight blue discolouration of an extremity
severe pain in your stomach (acute abdomen)
What are you possibly suffering from?
Blood clots blocking other blood vessels
See a doctor as soon as possible. Do not take any more Microgynon 30 until your doctor says you can. Use another method of contraception, such as condoms, in the meantime.
BLOOD CLOTS IN A VEIN
What can happen if a blood clot forms in a vein?
The use of combined hormonal contraceptives has been connected with an increase in the risk of blood clots in the vein (venous thrombosis). However, these side effects are rare. Most frequently, they occur in the first year of use of a combined hormonal contraceptive.
If a blood clot forms in a vein in the leg or foot it can cause a deep vein thrombosis (DVT).
If a blood clot travels from the leg and lodges in the lung it can cause a pulmonary embolism.
Very rarely a clot may form in a vein in another organ such as the eye (retinal vein thrombosis).
When is the risk of developing a blood clot in a vein highest?
The risk of developing a blood clot in a vein is highest during the first year of taking a combined hormonal contraceptive for the first time. The risk may also be higher if you restart taking a combined hormonal contraceptive (the same product or a different product) after a break of 4 weeks or more.
After the first year, the risk gets smaller but is always slightly higher than if you were not using a combined hormonal contraceptive.
When you stop Microgynon 30 your risk of a blood clot returns to normal within a few weeks.
What is the risk of developing a blood clot?
The risk depends on your natural risk of VTE and the type of combined hormonal contraceptive you are taking.
The overall risk of a blood clot in the leg or lung (DVT or PE) with Microgynon 30 is small.
Out of 10,000 women who are not using any combined hormonal contraceptive and are not pregnant, about 2 will develop a blood clot in a year.
Out of 10,000 women who are using a combined hormonal contraceptive that contains levonorgestrel, such as Microgynon 30, about 5-7 will develop a blood clot in a year.
The risk of having a blood clot will vary according to your personal medical history (see “Factors that increase your risk of a blood clot in a vein” below).
Women who are not using a combined hormonal pill and are not pregnant
Risk of developing a blood clot in a year - About 2 out of 10,000 women
Women using a combined hormonal contraceptive pill containing levonorgestrel
Risk of developing a blood clot in a year - About 5-7 out of 10,000 women
Women using Microgynon 30
Risk of developing a blood clot in a year - About 5-7 out of 10,000 women
Factors that increase your risk of a blood clot in a vein
The risk of a blood clot with Microgynon 30 is small but some conditions will increase the risk. Your risk is higher:
if you are very overweight (body mass index or BMI over 30kg/m2)
if one of your immediate family has had a blood clot in the leg, lung or other organ at a young age (e.g. below the age of about 50). In this case you could have a hereditary blood clotting disorder
if you need to have an operation, or if you are off your feet for a long time because of an injury or illness, or you have your leg in a cast. The use of Microgynon 30 may need to be stopped several weeks before surgery or while you are less mobile. If you need to stop Microgynon 30 ask your doctor when you can start using it again.
as you get older (particularly above about 35 years)
if you gave birth less than a few weeks ago.
The risk of developing a blood clot increases the more conditions you have.
Air travel (&4 hours) may temporarily increase your risk of a blood clot, particularly if you have some of the other factors listed.
It is important to tell your doctor if any of these conditions apply to you, even if you are unsure. Your doctor may decide that Microgynon 30 needs to be stopped.
If any of the above conditions change while you are using Microgynon 30, for example a close family member experiences a thrombosis for no known reason, or you gain a lot of weight, tell your doctor.
BLOOD CLOTS IN AN ARTERY
What can happen if a blood clot forms in an artery?
Like a blood clot in a vein, a clot in an artery can cause serious problems. For example, it can cause a heart attack or a stroke.
Factors that increase your risk of a blood clot in an artery
It is important to note that the risk of a heart attack or stroke from using Microgynon 30 is very small but can increase:
with increasing age (beyond about 35 years)
if you smoke. When using a combined hormonal contraceptive like Microgynon 30, you are advised to stop smoking. If you are unable to stop smoking and are older than 35 your doctor may advise you to use a different type of contraceptive
if you are overweight
if you have high blood pressure
if a member of your immediate family has had a heart attack or stroke at a young age (less than about 50). In this case you could also have a higher risk of having a heart attack or stroke
if you, or someone in your immediate family, have a high level of fat in the blood (cholesterol or triglycerides)
if you get migraines, especially migraines with aura
if you have a problem with your heart (valve disorder, disturbance of the rhythm called atrial fibrillation)
if you have diabetes.
If you have more than one of these conditions or if any of them are particularly severe the risk of developing a blood clot may be increased even more.
If any of the above conditions change while you are using Microgynon 30, for example you start smoking, a close family member experiences a thrombosis for no known reason, or you gain a lot of weight, tell your doctor.
While high dose Pills reduce your risk of cancer of the ovary and womb if used in the long term, it is not clear whether lower dose Pills like Microgynon 30 also provide the same protective effects. However, it also seems that taking the Pill slightly increases your risk of cancer of the cervix – although this may be due to having sex without a condom, rather than the Pill. All women should have regular smear tests.
If you have breast cancer, or have had it in the past, you should not take the Pill. The Pill slightly increases your risk of breast cancer. This risk goes up the longer you’re on the Pill, but returns to normal within about 10 years of stopping it. Because breast cancer is rare in women under the age of 40, the extra cases of breast cancer in current and recent Pill users is small. For example:
Of 10,000 women who have never taken the Pill, about 16 will have breast cancer by the time they are 35 years old.
Of 10,000 women who take the Pill for 5 years in their early twenties, about 17–18 will have breast cancer by the time they are 35 years old.
Of 10,000 women who have never taken the Pill, about 100 will have breast cancer by the time they are 45 years old.
Of 10,000 women who take the Pill for 5 years in their early thirties, about 110 will have breast cancer by the time they are 45 years old.
Your risk of breast cancer is higher:
if you have a close relative (mother, sister or grandmother) who has had breast cancer
if you are seriously overweight
See a doctor as soon as possible if you notice any changes in your breasts, such as dimpling of the skin, changes in the nipple or any lumps you can see or feel.
Taking the Pill has also been linked to liver diseases, such as jaundice and non-cancer liver tumours, but this is rare. Very rarely, the Pill has also been linked with some forms of liver cancer in women who have taken it for a long time.
See a doctor as soon as possible if you get severe pain in your stomach, or yellow skin or eyes (jaundice). You may need to stop taking Microgynon 30.
If you ever need to take another medicine at the same time as being on the Pill, always tell your doctor, pharmacist or dentist that you’re taking Microgynon 30. Also check the leaflets that come with all your medicines to see if they can be taken with hormonal contraceptives.
Some medicines can have an influence on the blood levels of Microgynon 30 and can stop it from working properly – for example:
some medicines used to treat epilepsy
some medicines used to treat HIV and Hepatitis C Virus infections (so-called protease inhibitors and non-nucleoside reverse transcriptase inhibitors)
griseofulvin (an anti-fungal medicine)
certain antibiotics
certain sedatives (called barbiturates)
St. John’s Wort (a herbal remedy).
If you do need to take one of these medicines, Microgynon 30 may not be suitable for you or you may need to use extra contraception for a while. Your doctor, pharmacist or dentist can tell you if this is necessary and for how long.
Microgynon 30 can also affect how well other medicines work. Your doctor may need to adjust the dose of your other medicine.
In addition, Microgynon 30 can also interfere with the results of some blood tests, so always tell your doctor that you are taking Microgynon 30 if you have a blood test.
There are no special instructions about food and drink while on Microgynon 30.
Do not use Microgynon 30 if you are pregnant. If you think you might be pregnant, do a pregnancy test to confirm that you are before you stop taking Microgynon 30.
If you are breast-feeding, your doctor or family planning nurse may advise you not to take Microgynon 30. They will be able to suggest alternative contraception. Breast-feeding may not stop you getting pregnant.
Microgynon 30 has no known effect on the ability to drive or use machines.
If you have been told by your doctor that you have intolerance to some sugars, contact your doctor before using Microgynon 30.
To prevent pregnancy, always take Microgynon 30 as described below. Check with your doctor or family planning nurse if you are not sure.
Take Microgynon 30 every day for 21 days
Microgynon 30 comes in strips of 21 pills, each marked with a day of the week.
Take your pill at the same time every day.
Start by taking a pill marked with the correct day of the week.
Follow the direction of the arrows on the strip. Take one pill each day, until you have finished all 21 pills.
Swallow each pill whole, with water if necessary. Do not chew the pill.
Then have seven pill-free days
After you have taken all 21 pills in the strip, you have seven days when you take no pills. So if you take the last pill of one pack on a Friday, you will take the first pill of your next pack on the Saturday of the following week.
Within a few days of taking the last pill from the strip, you should have a withdrawal bleed like a period. This bleed may not have finished when it is time to start your next strip of pills.
You don’t need to use extra contraception during these seven pill-free days – as long as you have taken your pills correctly and start the next strip of pills on time.
Then start your next strip
Start taking your next strip of Microgynon 30 after the seven pill-free days – even if you are still bleeding. Always start the new strip on time.
As long as you take Microgynon 30 correctly, you will always start each new strip on the same day of the week.
As a new user or starting the Pill again after a break
It is best to take your first Microgynon 30 pill on the first day of your next period. By starting in this way, you will have contraceptive protection with your first pill.
Changing to Microgynon 30 from another contraceptive Pill
If you are currently taking a 21-day Pill: start Microgynon 30 the next day after the end of the previous strip. You will have contraceptive protection with your first pill. You will not have a bleed until after your first strip of Microgynon 30.
If you are taking a 28-day Pill: start taking Microgynon 30 the day after your last active pill. You will have contraceptive protection with your first pill. You will not have a bleed until after your first strip of Microgynon 30.
Or, if you are taking a progestogen-only Pill (POP or ‘mini Pill’): start Microgynon 30 on the first day of bleeding, even if you have already taken the progestogen-only Pill for that day. You will have contraceptive cover straight away.
Starting Microgynon 30 after a miscarriage or abortion
If you have had a miscarriage or an abortion during the first three months of pregnancy, your doctor may tell you to start taking Microgynon 30 straight away. This means that you will have contraceptive protection with your first pill.
If you have had a miscarriage or an abortion after the third month of pregnancy, ask your doctor for advice. You may need to use extra contraception, such as condoms, for a short time.
Contraception after having a baby
If you have just had a baby, your doctor may advise you that Microgynon 30 should be started 21 days after delivery provided that you are fully mobile. You do not have to wait for a period. You will need to use another method of contraception, such as a condom, until you start Microgynon 30 and for the first 7 days of pill taking.
If you miss a pill, follow these instructions:
When were you due to take the missed pill?
Less than 12 hours ago
Take the delayed pill straight away and further pills as usual. This may mean taking two pills in one day.
Don’t worry, your contraceptive protection should not be reduced.
More than 12 hours ago, or you have missed more than one pill.
Take the most recently missed pill straight away.
Leave any earlier missed pills in the strip.
Take your further pills as usual. This may mean taking two pills in one day.
Use extra precautions (condoms, for instance) for the next 7 days.
Check how many pills are left in the strip after the most recently missed pill.
7 or more pills left in the pack
Don’t forget to use extra precautions for the next 7 days.
When you have finished the strip, leave the usual 7-day break before starting the next strip.
If you have missed one or more pills from the first week of your strip (days 1 to 7) and you had sex in that week, you could become pregnant. Contact your doctor, family planning nurse or pharmacist for advice as soon as possible. They may recommend you use emergency contraception.
Fewer than 7 pills left in the pack
Don’t forget to use extra precautions for the next 7 days.
When you finish the strip of pills, start the next strip the next day without a break.
If you do not have a withdrawal bleed after you have finished the second strip, do a pregnancy test before starting another strip.
If you have missed one or more pills from the first week of your strip (days 1 to 7) and you had sex in that week, you could become pregnant. Contact your doctor, family planning nurse or pharmacist for advice as soon as possible.
If you have missed any of the pills in a strip, and you do not bleed in the first pill-free break, you may be pregnant. Contact your doctor or family planning clinic, or do a pregnancy test yourself.
If you start a new strip of pills late, or make your ‘week off’ longer than seven days, you may not be protected from pregnancy. If you had sex in the last seven days, ask your doctor, family planning nurse or pharmacist for advice. You may need to consider emergency contraception. You should also use extra contraception, such as a condom, for seven days.
If you lose a pill,
Either take the last pill of the strip in place of the lost pill. Then take all the other pills on their proper days. Your cycle will be one day shorter than normal, but your contraceptive protection won’t be affected. After your seven pill-free days you will have a new starting day, one day earlier than before.
Or if you do not want to change the starting day of your cycle, take a pill from a spare strip if you have one. Then take all the other pills from your current strip as usual. You can then keep the opened spare strip in case you lose any more pills.
If you are sick (vomit) or have very bad diarrhoea within 4 hours of taking the Pill, your body may not get its usual dose of hormones from that pill. If you are better within 12 hours of taking Microgynon 30, follow the instructions in section 3.4 A lost pill, which describes how to take another pill.
If you are still sick or have diarrhoea more than 12 hours after taking Microgynon 30, see section 3.3, A missed pill.
Talk to your doctor if your stomach upset carries on or gets worse. He or she may recommend another form of contraception.
Occasionally, you may miss a withdrawal bleed. This could mean that you are pregnant, but that is very unlikely if you have taken your pills correctly. Start your next strip at the normal time. If you think that you might have put yourself at risk of pregnancy (for example, by missing pills or taking other medicines), or if you miss a second bleed, you should do a pregnancy test. You can buy these from the chemist or get a free test at your family planning clinic or doctors surgery. If you are pregnant, stop taking Microgynon 30 and see your doctor.
It is unlikely that taking more than one pill will do you any harm, but you may feel sick, vomit or have some vaginal bleeding. Talk to your doctor if you have any of these symptoms.
If you are planning a baby, it’s best to use another method of contraception after stopping Microgynon 30 until you have had a proper period. Your doctor or midwife relies on the date of your last natural period to tell you when your baby is due. However, it will not cause you or the baby any harm if you get pregnant straight away.
Like all medicines, Microgynon 30 can cause side effects, although not everybody gets them. . If you get any side effect, particularly if severe and persistent, or have any change to your health that you think may be due to Microgynon 30, please talk to your doctor.
An increased risk of blood clots in the veins (venous thromboembolism (VTE)) or blood clots in the arteries (arterial thromboembolism (ATE)) is present for all women using combined hormonal contraceptives. For more detailed information on the different risks from taking combined hormonal contraceptives please see section 2 “What you need to know before you use Microgynon 30”.
Tell your doctor, pharmacist or family planning nurse if you are worried about any side effects which you think may be due to Microgynon 30.
Rare side effects (between 1 and 10 in every 10,000 users may be affected)
harmful blood clots in a vein or artery for example:
in a leg or foot (i.e. DVT)
in a lung (i.e. PE)
heart attack
mini-stroke or temporary stroke-like symptoms, known as a transient ischaemic attack (TIA)
blood clots in the liver, stomach/intestine, kidneys or eye.
The chance of having a blood clot may be higher if you have any other conditions that increase this risk (see section 2 for more information on the conditions that increase risk for blood clots and the symptoms of a blood clot).
Signs of a blood clot (see section 2.3 ‘Blood clots’)
Signs of a severe allergic reaction or worsening of hereditary angioedema:
swelling of the hands, face, lips, mouth, tongue or throat. A swollen tongue/throat may lead to difficulty swallowing and breathing
a red bumpy rash (hives) and itching.
Signs of breast cancer include:
dimpling of the skin
changes in the nipple
any lumps you can see or feel.
Signs of cancer of the cervix include:
vaginal discharge that smells and/or contains blood
unusual vaginal bleeding
pelvic pain
painful sex.
Signs of severe liver problems include:
severe pain in your upper abdomen
yellow skin or eyes (jaundice)
inflammation of the liver (hepatitis)
your whole body starts itching.
If you think you may have any of these, see a doctor straight away. You may need to stop taking Microgynon 30.
Common side effects (between 100 and 1000 in every 10,000 users may be affected)
feeling sick
stomach ache
putting on weight
depressive moods or mood swings
sore or painful breasts
Uncommon side effects (between 10 and 100 in every 10,000 users may be affected)
being sick and stomach upsets
fluid retention
loss of interest in sex
breast enlargement
skin rash, which may be itchy
Rare side effects (between 1 and 10 in every 10,000 users may be affected)
poor tolerance of contact lenses
losing weight
increase of interest in sex
vaginal or breast discharge
Other side effects reported
Bleeding and spotting between your periods can sometimes occur for the first few months but this usually stops once your body has adjusted to Microgynon 30. If it continues, becomes heavy or starts again, contact your doctor (see section 4.3).
Chloasma (yellow brown patches on the skin). This may happen even if you have been using Microgynon 30 for a number of months. Chloasma may be reduced by avoiding too much sunlight and/or UV lamps
Occurrence or deterioration of the movement disorder chorea
Crohn’s disease or ulcerative colitis
Conditions that may worsen during pregnancy or previous use of the Pill:
yellowing of the skin (jaundice)
persistent itching (pruritus)
kidney or liver problems
gall stones
certain rare medical conditions such as systemic lupus erythematosus
blister-like rash (herpes gestationis) whilst pregnant
an inherited form of deafness (otosclerosis)
a personal or family history of a form of sickle cell disease
swelling of body parts (hereditary angioedema)
an inherited disease called porphyria
cancer of the cervix
Tell your doctor, pharmacist or family planning nurse if you are worried about any side effects which you think may be due to Microgynon 30. Also tell them if any existing conditions get worse while you are taking Microgynon 30.
A few women have a little unexpected bleeding or spotting while they are taking Microgynon 30, especially during the first few months. Normally, this bleeding is nothing to worry about and will stop after a day or two. Keep taking Microgynon 30 as usual. The problem should disappear after the first few strips.
You may also have unexpected bleeding if you are not taking your pills regularly, so try to take your pill at the same time every day. Also, unexpected bleeding can sometimes be caused by other medicines.
Make an appointment to see your doctor if you get breakthrough bleeding or spotting that:
carries on for more than the first few months
starts after you’ve been taking Microgynon 30 for a while
carries on even after you’ve stopped taking Microgynon 30.
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard.
By reporting side effects you can help provide more information on the safety of this medicine.
Keep all medicines out of the sight and reach of children.
Do not use Microgynon 30 after the expiry date shown on the strip.
Do not throw away any medicines down a drain or into a bin. Ask your pharmacist what to do with any medicines you do not want. This will help to protect the environment.
Each box of Microgynon 30 contains three strips of 21 beige tablets.
Each beige sugar-coated tablet contains: 150 micrograms of the progestogen levonorgestrel, and 30 micrograms of the oestrogen ethinylestradiol.
Microgynon 30 also contains the inactive ingredients:
Lactose, maize starch, povidone, magnesium stearate (E572), sucrose, macrogol 6000, calcium carbonate (E170), talc, montan glycol wax, titanium dioxide (E171), glycerin (E422), ferric oxide pigment yellow (E172).
Bayer plcBayer HouseStrawberry HillNewburyBerkshireRG14 1JA
Bayer Pharma AGBerlinGermany
Bayer Weimar GmbH & Co KGWeimarGermany
Delpharm Lille SASLys-Lez-LannoyFrance
This leaflet was last updated in May 2015.
AddressBayer House, Strawberry Hill, Newbury, Berkshire, RG14 1JA
Fax+44 (0)
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Before you contact this company: often several companies will market medicines with the same active ingredient. Please check that this is the correct company before contacting them.
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