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抑癌基因Rbms3抗体
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产品详细说明
产品规格：0.2ml/200μg
牌：抗体行业知名品牌
地：美、德及中国大陆
产品包装：管装
格：1元/克
抑癌基因Rbms3抗体
&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&
交叉反应& Human, Mouse, Rat, Chicken, Dog, Cow, Horse& &&&&&&&&&
产品类型& 一抗&&& &&&&&&&&&
研究领域& 免疫学 染色质和核信号 结合蛋白 表观遗传学& &&&&&&&&&
蛋白分子量& predicted molecular weight: 48kDa &&&&&&&&&
性&&& 状& Lyophilized or Liquid&&&&&&&&&&
抑癌基因Rbms3抗体
免 疫 原& KLH conjugated synthetic peptide derived from human Rbms3 C-terminus &&&&&&&&&
亚&&& 型& IgG &&&&&&&&&
纯化方法& affinity purified by Protein A &&&&&&&&&
储 存 液& 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide &&&&&&&&&
产品应用&& WB=1:100-500& ELISA=1:500-1000& IP=1:20-100& IHC-P=1:100-500& IHC-F=1:100-500& IF=1:100-500 &&&&&&&&&
（石蜡切片需做抗原修复） &&&&&&&&&
&not yet tested in other applications.&&&&&&&&&
&optimal dilutions/concentrations should be determined by the end user.& &&&&&&&&&
保存条件& Store at -20 &C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20&C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 &C. &&&&&&&&&
Important Note& This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. &&&&&&&&&
产品介绍 RBMS3 is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis.The protein encoded by this gene is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2(I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.&&&&&&&&&
Function : Binds poly(A) and poly(U) oligoribonucleotides. &&&&&&&&&
Subcellular Location : Cytoplasm.&&&&&&&&&
Tissue Specificity : Expressed in fetal brain, fetal lung, fetal liver, heart, brain, placenta, lung, liver, muscle, kidney and pancreas.&&&&&&&&&
Similarity : Contains 2 RRM (RNA recognition motif) domains.&&&&&&&&&
Database links : UniProtKB/Swiss-Prot: Q6XE24.1&&&&&&&&&&&
英文名称& Anti-Rbms3 &&&&&&&&&
中文名称& 抑癌基因Rbms3抗体&&&&&&&&&&
抑癌基因Rbms3抗体
别&&& 名& RBMS3_HUMAN; RNA binding motif, single stranded RNA binding motif, single stranded RNA binding motif, single stranded interacting protein 3; RNA binding protein. &&&&&&&&&
浓&&& 度& 1mg/1ml &&&&&&&&&
规 格& 0.1ml/100&g& 0.2ml/200&g&&&&&&&&&
抗体来源& Rabbit& &&&&&&&&&
克隆类型& polyclonal&&&&&&&&&&
抑癌基因Rbms3抗体
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版权声 明&2016美中现在有无创DNA么?_请问美中还有无创DNA么？如果有，_宝宝树
美中现在有无创DNA么?
请问美中还有无创DNA么？如果有，怎么收费？谢谢
有 2500 送华大检测
2500还包含个保险
有的！随时去就可以
什么是无创DNA，测宝宝性别吗？
你还小，到时候大夫会告诉你哒～～
回复 &默默爱麻麻爱默默&
14:26:29发表的
什么是无创DNA，测宝宝性别吗？
有，12周以上就可以做
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肿瘤抑制基因p63α抗体
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可销售总数量：
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建议零售价：
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请致电了解详情。
已通过企业实名备案
联&系&人：高玥 销售员
企业经济性质：私营有限责任公司
所&在&地&址：上海上海
详&细&地&址：上海市闵行区闵北路88弄1-17号、18-30号第13幢038室
上次登录时间：日
产品详细说明
产品规格：0.2ml/200μg
牌：抗体行业知名品牌
地：美、德及中国大陆
产品包装：管装
格：1元/克
肿瘤抑制基因p63&抗体
肿瘤抑制基因p63&抗体
肿瘤抑制基因p63&抗体
品牌&&&&&&&&&&&&&&&&&&&&
英文名称& Anti-P63 protein/P51A &&&&&&&&&&&&
中文名称& 肿瘤抑制基因p63&抗体&&&&&&&&&&&&&
肿瘤抑制基因p63&抗体
别&&& 名& AIS; Amplified in squ B(p51A); B(p51B); p63 A Chronic ulcerativ CUSP; DN p63 alpha 1; DNp63; EEC3; Keratinocyte
Keratinocyte transcription factor KET; KET; LMS; NBP; OFC8; p40; p51; P51/P63; p53 like
p53 p53-related protein p63; p53CP; p63; P73; p73H; p73L; RHS; SHFM4; TP53CP; TP53L; TP63; TP73; TP73L; Transformation related protein 63; Trp53rp1; Trp63; Tumor protein 63; tumor protein 63 kDa with strong homology to p53; Tumor protein p53- Tumor protein p53- tumor protein p63; Tumor protein p73; tumor protein p73- P63_HUMAN. &&&&&&&&&&&&
浓&&& 度& 1mg/1ml &&&&&&&&&&&&
规 格& 0.1ml/100&g& 0.2ml/200&g &&&&&&&&&&&&
抗体来源& Rabbit& &&&&&&&&&&&&
克隆类型& polyclonal &&&&&&&&&&&&
交叉反应& Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig&&&&&&&&&&&&
产品类型& 一抗&&& &&&&&&&&&&&&
研究领域& 肿瘤 细胞生物 免疫学 信号转导 转录调节因子& &&&&&&&&&&&&
蛋白分子量& predicted molecular weight: 77kDa &&&&&&&&&&&&
性&&& 状& Lyophilized or Liquid &&&&&&&&&&&&
免 疫 原& KLH conjugated synthetic peptide derived from human P63 protein &&&&&&&&&&&&
亚&&& 型& IgG &&&&&&&&&&&&
纯化方法& affinity purified by Protein A &&&&&&&&&&&&
储 存 液& 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide &&&&&&&&&&&&
产品应用&& WB=1:100-500& ELISA=1:500-1000& IP=1:20-100& IHC-P=1:100-500& IHC-F=1:100-500& ICC=1:100-500& IF=1:100-500 &&&&&&&&&&&&
（石蜡切片需做抗原修复） &&&&&&&&&&&&
&not yet tested in other applications.&&&&&&&&&&&&
&optimal dilutions/concentrations should be determined by the end user.& &&&&&&&&&&&&
保存条件& Store at -20 &C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20&C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 &C. &&&&&&&&&&&&
Important Note& This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. &&&&&&&&&&&&
产品介绍 This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/ ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb- Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined. [provided by RefSeq, Jul 2008].&&&&&&&&&&&&
Function : Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge.&&&&&&&&&&&&
Subunit : Binds DNA as a homotetramer. Isoform composition of the tetramer may determine transactivation activity. Isoforms Alpha and Gamma interact with HIPK2. Interacts with SSRP1, leading to stimulate coactivator activity. Isoform 1 and isoform 2 interact with WWP1. Interacts with PDS5A. Isoform 5 (via activation domain) interacts with NOC2L.&&&&&&&&&&&&
Subcellular Location : Nucleus.&&&&&&&&&&&&
Tissue Specificity : Widely expressed, notably in heart, kidney, placenta, prostate, skeletal muscle, testis and thymus, although the precise isoform varies according to tissue type. Progenitor cell layers of skin, breast, eye and prostate express high levels of DeltaN-type isoforms. Isoform 10 is predominantly expressed in skin squamous cell carcinomas, but not in normal skin tissues.&&&&&&&&&&&&
Post-translational modifications : May be sumoylated.&&&&&&&&&&&&
Ubiquitinated. Polyubiquitination involves WWP1 and leads to proteasomal degradation of this protein.&&&&&&&&&&&&
DISEASE : Defects in TP63 are the cause of acro-dermato-ungual-lacrimal-tooth syndrome (ADULT syndrome) [MIM:103285]; a form of ectodermal dysplasia. Ectodermal dysplasias (EDs) constitute a heterogeneous group of developmental disorders affecting tissues of ectodermal origin. EDs are characterized by abnormal development of two or more ectodermal structures such as hair, teeth, nails and sweat glands, with or without any additional clinical sign. Each combination of clinical features represents a different type of ectodermal dysplasia. ADULT syndrome involves ectrodactyly, syndactyly, finger- and toenail dysplasia, hypoplastic breasts and nipples, intensive freckling, lacrimal duct atresia, frontal alopecia, primary hypodontia, and loss of permanent teeth. ADULT differs significantly from EEC3 syndrome by the absence of facial clefting. &&&&&&&&&&&&
Similarity : Belongs to the p53 family.&&&&&&&&&&&&
Contains 1 SAM (sterile alpha motif) domain.&&&&&&&&&&&&
Database links : UniProtKB/Swiss-Prot: Q9H3D4.1&&&&&&&&&&&&
P63&也是肿瘤抑制因子之一.p63基因是抑癌基因p53的同源性基因，主要表达上皮组织的基底细胞或复层上皮细胞，如皮肤、食道、宫颈外口、扁桃体、膀胱等，和前列腺、乳腺腺样结构的基层细胞。
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Y109720&溶质载体家族39成员6(SLC39A6)检测试剂盒(酶联免疫吸附试验法)&ELISA Kit for Solute Carrier Family 39, Member 6 (SLC39A6)&48T/96T&Homo sapiens (Human)&
Y109721&接触蛋白关联蛋白样蛋白2(CNTNAP2)检测试剂盒(酶联免疫吸附试验法)&ELISA Kit for Contactin Associated Protein Like Protein 2 (CNTNAP2)&48T/96T&Homo sapiens (Human)&
Y109722&神经蛋白聚糖(NCAN)检测试剂盒(酶联免疫吸附试验法)&ELISA Kit for Neurocan (NCAN)&48T/96T&Rattus norvegicus (Rat)&
Y109723&细胞因子信号转导抑制因子3(SOCS3)检测试剂盒(酶联免疫吸附试验法)&ELISA Kit for Suppressors Of Cytokine Signaling 3 (SOCS3)&48T/96T&Rattus norvegicus (Rat)&
Y109724&葡萄糖6磷酸异构酶(GPI)检测试剂盒(酶联免疫吸附试验法)&ELISA Kit for Glucose 6 Phosphate Isomerase (GPI)&48T/96T&Rattus norvegicus (Rat)&
Y109725&皮屑蛋白样蛋白1(LEPREL1)检测试剂盒(酶联免疫吸附试验法)&ELISA Kit for Leprecan Like Protein 1 (LEPREL1)&48T/96T&Homo sapiens (Human)&
Y109726&动力蛋白胞浆1重链1(DYNC1H1)检测试剂盒(酶联免疫吸附试验法)&ELISA Kit for Dynein, Cytoplasmic 1, Heavy Chain 1 (DYNC1H1)&48T/96T&Homo sapiens (Human)&
Y109727&突触融合蛋白1A(STX1A)检测试剂盒(酶联免疫吸附试验法)&ELISA Kit for Syntaxin 1A, Brain (STX1A)&48T/96T&Homo sapiens (Human)&
Y109728&补体成分5a受体1(C5aR1)检测试剂盒(酶联免疫吸附试验法)&ELISA Kit for Complement Component 5a Receptor 1 (C5aR1)&48T/96T&Mus musculus (Mouse)&
Y109729&蛋白L-异天冬氨酸-O-甲基转移酶(PCMT1)检测试剂盒(酶联免疫吸附试验法)&ELISA Kit for Protein L-Isoaspartate-O-Methyltransferase (PCMT1)&48T/96T&Homo sapiens (Human)&
Y109730&二氢乳清酸脱氢酶(DHODH)检测试剂盒(酶联免疫吸附试验法)&ELISA Kit for Dihydroorotate Dehydrogenase (DHODH)&48T/96T&Mus musculus (Mouse)&
Y109731&肿瘤坏死因子受体超家族成员1B(TNFRSF1B)检测试剂盒(酶联免疫吸附试验法)&ELISA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B)&48T/96T&Homo sapiens (Human)&
Y109732&整合素&3(ITG&3)检测试剂盒(酶联免疫吸附试验法)&ELISA Kit for Integrin Beta 3 (ITGb3)&48T/96T&Mus musculus (Mouse)&
Y109733&Disabled同源物1(DAB1)检测试剂盒(酶联免疫吸附试验法)&
肿瘤抑制基因p63&抗体
ELISA Kit for Disabled Homolog 1 (DAB1)&48T/96T&Rattus norvegicus (Rat)&
肿瘤抑制基因p63&抗体
说明简要部分，如果需要
肿瘤抑制基因p63&抗体
说明书，请来电索取。
上海研域商贸有限公司总部设在上海，公司专业经营生命科学领域的研究试剂、实验室消耗品等，我们致力于向国内外生命科学研究人员提供一流的产品和技术服务。 我们代理和经销的分子生物学试剂、生化试剂、免疫试剂、ELISA试剂盒、细胞株、培养基、胎牛血清、抗体、标准品、对照品等试剂产品，已被广泛应用于生命科学基础与开发研究、生化领域、生物技术等诸多领域。我们长期积累的客户已遍布国内外各地大学、研究所、医院、国家重点实验室等单位。 我们的宗旨是为了中国生命科学事业的腾飞，我们全力以赴，以更好的品质、更优惠的价格、更专业的技术服务好每一位客户的需求。
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