非结核分枝杆菌抗体阳性Runyon分类有几群?每群各举2例。

来源：蜘蛛抓取(WebSpider) 时间：2015-01-19 20:25 标签： 非结核分枝杆菌肺病
非结核分枝杆菌Runyon分类有几群?每群各举2例。
非结核分校杆菌Runyon分类有四群:
(1)堪萨斯分枝杆菌、海分枝杆菌。 (2)瘰疬痴分枝杆菌、苏尔加分枝杆菌。 (3)鸟-胞内复合分校杆菌、蟾分枝杆菌。 (4)偶发分枝杆、龟分枝杆菌。
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扫描下载二维码Comparison of the Simplify D-dimer assay performed at the bedside with a laboratory-based quantitative D-dimer assay for the
diagnosis of pulmonary embolism in a low prevalence emergency department population -- Runyon et al. 25 (2): 70 -- Emergency
Medicine Journal
An international peer-reviewed journal
for health professionals and researchers in emergency medicine
Emerg Med J
doi:10.1136/emj.
1Department of Emergency Medicine, Carolinas Medical Center, Charlotte, North Carolina, USA
2Department of Pathology, Carolinas Medical Center, Charlotte, North Carolina, USA
Dr J A Kline, Emergency Medicine Research, Department of Emergency Medicine, Carolinas Medical Center, PO Box 32861, Charlotte,
North Carolina , USA; jkline{at}carolinas.org
Accepted 24 July 2007
Background: The immunofiltration D-dimer assay could allow point-of-care testing for pulmonary embolism (PE). A study was undertaken
to compare a clinician-performed qualitative D-dimer assay with the automated quantitative D-dimer test.
Methods: A prospective observational study was conducted from January to October 2005 at an urban academic emergency department (ED).
1193 patients of mean (SD) age 47 (16) years (66% female) were enrolled. The study protocol combined pretest probability estimation,
D-dimer testing by both a qualitative immunochromatographic assay (Simplify) performed at the point of care by 192 different
clinicians and a quantitative D-dimer test performed in a CLIA-certified laboratory. The criterion standard was image-proven
PE or deep venous thrombosis within 45 days after enrolment. To test interobserver agreement for the qualitative assay, two
blinded observers independently read 841 Simplify cartridges.
Results: Of 1193 patients enrolled, 45 were PE+ (3.8%, 95% CI 2.8% to 5.0%). Qualitative results were available for 1169 (98%) and
quantitative results were available for 1136 (95%). Comparison of the qualitative and quantitative D-dimer tests gave the
following results: sensitivity 91% (95% CI 78% to 98%) vs 93% (95% CI 80% to 98%); specificity 57% (95% CI 54% to 60%) vs
57% (95% CI 54% to 60%); likelihood ratio negative 0.16 (95% CI 0.06 to 0.37) vs 0.13 (95% CI 0.05 to 0.35). The weighted
Cohen’s κ for interpretation of the qualitative assay was 0.69 (95% CI 0.63 to 0.76).
Conclusions: In this very low-risk ED population, a qualitative D-dimer assay performed at the point of care had similar diagnostic accuracy
to the quantitative D-dimer test. Interobserver agreement for the qualitative test was good.
Competing interests: JAK owns stock in BreathQuant Medical LLC and Pretest Consult LLC. The other authors have no competing interests.
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Simon Carley
Emerg Med J 25:2 63
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