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PREDICTED: DNA replication licensing factor MCM5 [Oryctolagus cuniculus]
Graphical summary
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List of domain hits
MCM N- This family contains the N-terminal region of MCM proteins. This region ...
....*....|....*....|....*....|....*....|...
<font color=# TRPRPAGDEAlQDIQVMLKSDASPSSVRSLKSDMMSHLVKIPG <font color=#
<font color=# DPFPPELKRR-KEIQVRFYNLPKVVSIRDLRSSHIGKLVSVEG <font color=#
minichromosome
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# dPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIK--KFGLTSTRGRDRVGV <font color=#
<font color=# -PFSLNHERSTFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVpyGFKLNTVKGLPVFAT <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# GIRSSYIRVLGIQVDTDGSGRSFaGSVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPD <font color=#
<font color=# YIEANHVRKLDYKRSFEDSSFSV-QSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPD <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# GLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEF <font color=#
<font color=# GMKIRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEF <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# DKMREDDRVAIHEAMEQQTISLAKAGITTTLNSRCSVLAAANSVFGRWDETKG-EDNIDFMPTILSRFDMIFIVKDEHNE <font color=#
<font color=# DKMDDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTpEENIDLPAPILSRFDLLFVVLDEVDE <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# ERDVMLAKHVITLHV-SALTQTQAVEGEIDLAKLKKFIAYCRAKCGPRLSAEAAEKLKNRYIIMrsgaRQHERDSARRSS <font color=#
<font color=# ERDRELAKHVVDLHRySHPEEDEAFEPPLSQEKLRKYIAYAREKIKPKLSEEAADKLVKAYVDL----RKEDSQTESRSS <font color=#
....*....|....*....|....*....|....*....|....
<font color=# IPITVRQLEAIVRISEALSKMKLQPFATEADVEEALRLFQVSTL <font color=#
<font color=# IPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII <font color=#
MCM N- This family contains the N-terminal region of MCM proteins. This region ...
....*....|....*....|....*....|....*....|...
<font color=# TRPRPAGDEAlQDIQVMLKSDASPSSVRSLKSDMMSHLVKIPG <font color=#
<font color=# DPFPPELKRR-KEIQVRFYNLPKVVSIRDLRSSHIGKLVSVEG <font color=#
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ...
minichromosome
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# dPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIK--KFGLTSTRGRDRVGV <font color=#
<font color=# -PFSLNHERSTFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVpyGFKLNTVKGLPVFAT <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# GIRSSYIRVLGIQVDTDGSGRSFaGSVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPD <font color=#
<font color=# YIEANHVRKLDYKRSFEDSSFSV-QSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPD <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# GLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEF <font color=#
<font color=# GMKIRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEF <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# DKMREDDRVAIHEAMEQQTISLAKAGITTTLNSRCSVLAAANSVFGRWDETKG-EDNIDFMPTILSRFDMIFIVKDEHNE <font color=#
<font color=# DKMDDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTpEENIDLPAPILSRFDLLFVVLDEVDE <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# ERDVMLAKHVITLHV-SALTQTQAVEGEIDLAKLKKFIAYCRAKCGPRLSAEAAEKLKNRYIIMrsgaRQHERDSARRSS <font color=#
<font color=# ERDRELAKHVVDLHRySHPEEDEAFEPPLSQEKLRKYIAYAREKIKPKLSEEAADKLVKAYVDL----RKEDSQTESRSS <font color=#
....*....|....*....|....*....|....*....|....
<font color=# IPITVRQLEAIVRISEALSKMKLQPFATEADVEEALRLFQVSTL <font color=#
<font color=# IPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII <font color=#
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family
[Replication, recombination and ...
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# VMLKSDASPSSVRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLNNIAMRpglEGYALPRKCntdqagrP <font color=#
<font color=# VRFKNLPNRLSIRELRSEHIGKLVSVEGIVTRASEVRPRLKKAVFECPKCGREVEVEQSE---FRVEPPREC-------E <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# SCP---LDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKfgltstrgR <font color=#
<font color=# NCGkfgKGPLKLVPRKSEFIDFQKVKIQELPELVPGGELPRSIEVILEDDLVDSVRPGDRVKITGVVRIVP--------S <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# DRVGVGIRSSYIRVLGIQVDTDGSGRSFAGSVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSR <font color=#
<font color=# RSLSGRRKGPVFEIYLEANSVEKLDKREEVEITEEDEEEIKELAKRPDIYDILIKSIAPSIYGHEDVKKAILLQLFGGVK <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# KRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVV <font color=#
<font color=# KNLPDGTRIRGDIHILLVGDPGTAKSQLLKYVAKLAPRGVYTSGKGSSAAGLTAAVVRDKVTGEWVLEAGALVLADGGVC <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# CIDEFDKMREDDRVAIHEAMEQQTISLAKAGITTTLNSRCSVLAAANSVFGRWDETKGE-DNIDFMPTILSRFDMIFIVK <font color=#
<font color=# CIDEFDKMNEEDRVAIHEAMEQQTISIAKAGITATLNARCSVLAAANPKFGRYDPKKTVaENINLPAPLLSRFDLIFVLK <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# DEHNEERDVMLAKHVITLH--------VSALTQTQAVEGEIDLakLKKFIAYCRAKCGPRLSAEAAEKLKNRYIIMRSGA <font color=#
<font color=# DDPDEEKDEEIAEHILDKHrgeepeetISLDGVDEVEERDFEL--LRKYISYARKNVTPVLTEEAREELEDYYVEMRKKS <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# RQHErdsaRRSSIPITVRQLEAIVRISEALSKMKLQPFATEADVEEALRLFQVSTLDAAL---SGTLS-----GVEGFTS <font color=#
<font color=# ALVE----EKRTIPITARQLESIIRLAEAHAKMRLSDVVEEEDVDEAIRLVDFSLKTVAVdpeKGKIDidiiePGKSKSK <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*...
<font color=# QEDQEMLSRIEKQLKRRfaigsqvSEHSIVQDF-IKQKYPEHAVHKVLQLMLRRGEIQHRLQRKVLYR <font color=#
<font color=# RDKIEKVLDIIKELVER-------SEDPVEEIIeEAEGISEKEVEEALEKLKKKGDILEPNPGYYLLV <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# SPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISLAKAGITTT <font color=#
<font color=# APRAVYTSGKGSSAAGLTAAVVRDPDTGEWTLEAGALVLADGGVCCIDEFDKMNEEDRVAIHEAMEQQTISIAKAGIVAT <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# LNSRCSVLAAANSVFGRWDETKG-EDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHV-SALTQTQAVEGE-- <font color=#
<font color=# LNARCSVLAAANPIFGRYDPKKSvAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLHRnGEPSVEESIETEdy <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# IDLAKLKKFIAYCRAKCGPRLSAEAAEKLKNRYIIMRSgarqheRDSARRSSIPITVRQLEAIVRISEALSKMKLQPFAT <font color=#
<font color=# VDPELLRKYIAYARENIFPKLSEEAREKLVNYYVELRK------ESTGKRKSIPITVRQLESLIRLSEAHARLRLSEEVT <font color=#
....*....|....*
<font color=# EADVEEALRLFQVST <font color=#
<font color=# EEDVEEAIRLILESL <font color=#
DNA replication licensing factor MCM4; Provisional
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# LVKIPGIIIAASAVRAKATRISIQCRSCRntlnniamRPGLEGYalpRKCNTDQ-----AGRPSCPL--------DPYFI <font color=#
<font color=# LVQFSGTVVRQTWIVPEITMACFRCRGQK--------KIGLNDY---QPCTCEHyeyviQGEVNEPLlcnecnskYTFEL <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# MPDKCKCVDFQTLKLQELPDAVPHGEMPR----------------------HMQLYCDryLCDKVVPGNRVTIMGIYSIK <font color=#
<font color=# NHNMCVYSTKKIVKLLQSNSSLNNPDKDGldnsvdnsglngeiymkdneviNLNLYDD--LIDSVKTGDRVTVVGILKVT <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# KFGLTSTRgrdRVGVGIRSSYIRVLGIQV-DTDGSGRSFAGSVSPQEEEEF--------RRLAALPNVYEVISKSIAPSI <font color=#
<font color=# PIRTSTTR---RTLKSLYTYFVNVIHVKViNSTNANQPEKGLKYLGNENDFsdlqvykiLELSRNPMIYRILLDSFAPSI <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# FGGTDMKKAIACLLFGGSR-----KRLPDGLTR----RGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGL <font color=#
<font color=# KARNNVKIGLLCQLFSGNKnssdfNKSPDACYKvdnfRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGL <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# TASV-MRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISLAKAGITTTLNSRCSVLAAANSVFG <font color=#
<font color=# TASIkFNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINS <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# RWDETKGE-DNIDFMPTILSRFDMIFIVKDEHNEERD----VMLAKHVITLHVSAL---------TQTQAVEGEI----- <font color=#
<font color=# RYNKNKAViENINISPSLFTRFDLIYLVLDHIDQDTDqlisLSIAKDFLLPHMTGSgndedtydrSNTMHVEDESlrsek <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# -----DLAKLKKFIAYCRAKCGPRLSAEAAEKLKNRYIIMRSGARQ----HERDSARRS-------------SIPITVRQ <font color=#
<font color=# dynknDLDMLRMYIKFSKLHCFPKLSDEAKKVITREYVKMRQGNFQtsnlDELEHAQEDddddlyyqssgtrMIYVSSRM <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*
<font color=# LEAIVRISEALSKMKLQPFATEADVEEALRLFQVSTLDAALSGTLSGVE------GFTSQEDQEM <font color=#
<font color=# ISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTFQSLVDPTTGKIDfdqlhqGITTNKMQQL <font color=#
MCM N- This family contains the N-terminal region of MCM proteins. This region ...
....*....|....*....|....*....|....*....|...
<font color=# TRPRPAGDEAlQDIQVMLKSDASPSSVRSLKSDMMSHLVKIPG <font color=#
<font color=# DPFPPELKRR-KEIQVRFYNLPKVVSIRDLRSSHIGKLVSVEG <font color=#
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ...
minichromosome
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# dPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIK--KFGLTSTRGRDRVGV <font color=#
<font color=# -PFSLNHERSTFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVpyGFKLNTVKGLPVFAT <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# GIRSSYIRVLGIQVDTDGSGRSFaGSVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPD <font color=#
<font color=# YIEANHVRKLDYKRSFEDSSFSV-QSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPD <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# GLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEF <font color=#
<font color=# GMKIRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEF <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# DKMREDDRVAIHEAMEQQTISLAKAGITTTLNSRCSVLAAANSVFGRWDETKG-EDNIDFMPTILSRFDMIFIVKDEHNE <font color=#
<font color=# DKMDDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTpEENIDLPAPILSRFDLLFVVLDEVDE <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# ERDVMLAKHVITLHV-SALTQTQAVEGEIDLAKLKKFIAYCRAKCGPRLSAEAAEKLKNRYIIMrsgaRQHERDSARRSS <font color=#
<font color=# ERDRELAKHVVDLHRySHPEEDEAFEPPLSQEKLRKYIAYAREKIKPKLSEEAADKLVKAYVDL----RKEDSQTESRSS <font color=#
....*....|....*....|....*....|....*....|....
<font color=# IPITVRQLEAIVRISEALSKMKLQPFATEADVEEALRLFQVSTL <font color=#
<font color=# IPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII <font color=#
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family
[Replication, recombination and ...
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# VMLKSDASPSSVRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLNNIAMRpglEGYALPRKCntdqagrP <font color=#
<font color=# VRFKNLPNRLSIRELRSEHIGKLVSVEGIVTRASEVRPRLKKAVFECPKCGREVEVEQSE---FRVEPPREC-------E <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# SCP---LDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKfgltstrgR <font color=#
<font color=# NCGkfgKGPLKLVPRKSEFIDFQKVKIQELPELVPGGELPRSIEVILEDDLVDSVRPGDRVKITGVVRIVP--------S <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# DRVGVGIRSSYIRVLGIQVDTDGSGRSFAGSVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSR <font color=#
<font color=# RSLSGRRKGPVFEIYLEANSVEKLDKREEVEITEEDEEEIKELAKRPDIYDILIKSIAPSIYGHEDVKKAILLQLFGGVK <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# KRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVV <font color=#
<font color=# KNLPDGTRIRGDIHILLVGDPGTAKSQLLKYVAKLAPRGVYTSGKGSSAAGLTAAVVRDKVTGEWVLEAGALVLADGGVC <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# CIDEFDKMREDDRVAIHEAMEQQTISLAKAGITTTLNSRCSVLAAANSVFGRWDETKGE-DNIDFMPTILSRFDMIFIVK <font color=#
<font color=# CIDEFDKMNEEDRVAIHEAMEQQTISIAKAGITATLNARCSVLAAANPKFGRYDPKKTVaENINLPAPLLSRFDLIFVLK <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# DEHNEERDVMLAKHVITLH--------VSALTQTQAVEGEIDLakLKKFIAYCRAKCGPRLSAEAAEKLKNRYIIMRSGA <font color=#
<font color=# DDPDEEKDEEIAEHILDKHrgeepeetISLDGVDEVEERDFEL--LRKYISYARKNVTPVLTEEAREELEDYYVEMRKKS <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# RQHErdsaRRSSIPITVRQLEAIVRISEALSKMKLQPFATEADVEEALRLFQVSTLDAAL---SGTLS-----GVEGFTS <font color=#
<font color=# ALVE----EKRTIPITARQLESIIRLAEAHAKMRLSDVVEEEDVDEAIRLVDFSLKTVAVdpeKGKIDidiiePGKSKSK <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*...
<font color=# QEDQEMLSRIEKQLKRRfaigsqvSEHSIVQDF-IKQKYPEHAVHKVLQLMLRRGEIQHRLQRKVLYR <font color=#
<font color=# RDKIEKVLDIIKELVER-------SEDPVEEIIeEAEGISEKEVEEALEKLKKKGDILEPNPGYYLLV <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# SPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISLAKAGITTT <font color=#
<font color=# APRAVYTSGKGSSAAGLTAAVVRDPDTGEWTLEAGALVLADGGVCCIDEFDKMNEEDRVAIHEAMEQQTISIAKAGIVAT <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# LNSRCSVLAAANSVFGRWDETKG-EDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHV-SALTQTQAVEGE-- <font color=#
<font color=# LNARCSVLAAANPIFGRYDPKKSvAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLHRnGEPSVEESIETEdy <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# IDLAKLKKFIAYCRAKCGPRLSAEAAEKLKNRYIIMRSgarqheRDSARRSSIPITVRQLEAIVRISEALSKMKLQPFAT <font color=#
<font color=# VDPELLRKYIAYARENIFPKLSEEAREKLVNYYVELRK------ESTGKRKSIPITVRQLESLIRLSEAHARLRLSEEVT <font color=#
....*....|....*
<font color=# EADVEEALRLFQVST <font color=#
<font color=# EEDVEEAIRLILESL <font color=#
DNA replication licensing factor MCM4; Provisional
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# LVKIPGIIIAASAVRAKATRISIQCRSCRntlnniamRPGLEGYalpRKCNTDQ-----AGRPSCPL--------DPYFI <font color=#
<font color=# LVQFSGTVVRQTWIVPEITMACFRCRGQK--------KIGLNDY---QPCTCEHyeyviQGEVNEPLlcnecnskYTFEL <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# MPDKCKCVDFQTLKLQELPDAVPHGEMPR----------------------HMQLYCDryLCDKVVPGNRVTIMGIYSIK <font color=#
<font color=# NHNMCVYSTKKIVKLLQSNSSLNNPDKDGldnsvdnsglngeiymkdneviNLNLYDD--LIDSVKTGDRVTVVGILKVT <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# KFGLTSTRgrdRVGVGIRSSYIRVLGIQV-DTDGSGRSFAGSVSPQEEEEF--------RRLAALPNVYEVISKSIAPSI <font color=#
<font color=# PIRTSTTR---RTLKSLYTYFVNVIHVKViNSTNANQPEKGLKYLGNENDFsdlqvykiLELSRNPMIYRILLDSFAPSI <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# FGGTDMKKAIACLLFGGSR-----KRLPDGLTR----RGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGL <font color=#
<font color=# KARNNVKIGLLCQLFSGNKnssdfNKSPDACYKvdnfRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGL <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# TASV-MRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISLAKAGITTTLNSRCSVLAAANSVFG <font color=#
<font color=# TASIkFNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINS <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# RWDETKGE-DNIDFMPTILSRFDMIFIVKDEHNEERD----VMLAKHVITLHVSAL---------TQTQAVEGEI----- <font color=#
<font color=# RYNKNKAViENINISPSLFTRFDLIYLVLDHIDQDTDqlisLSIAKDFLLPHMTGSgndedtydrSNTMHVEDESlrsek <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# -----DLAKLKKFIAYCRAKCGPRLSAEAAEKLKNRYIIMRSGARQ----HERDSARRS-------------SIPITVRQ <font color=#
<font color=# dynknDLDMLRMYIKFSKLHCFPKLSDEAKKVITREYVKMRQGNFQtsnlDELEHAQEDddddlyyqssgtrMIYVSSRM <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*
<font color=# LEAIVRISEALSKMKLQPFATEADVEEALRLFQVSTLDAALSGTLSGVE------GFTSQEDQEM <font color=#
<font color=# ISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTFQSLVDPTTGKIDfdqlhqGITTNKMQQL <font color=#
MoxR-like ATPase [General function prediction only];
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# YTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISLakAGITT-TLNSR <font color=#
<font color=# TPDLLPSDLLGTYAYAALLLEPGEFRFVPGPLFAAVRVILLLDEINRAPPEVQNALLEALEERQVTV--PGLTTiRLPPP <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# CSVLAAANSVfgrwdETKGEDNIDfmPTILSRFDMIFIVK--DEHNEERDVMLAkhviTLHVSALTQTQAVEGEIDLAKL <font color=#
<font color=# FIVIATQNPG-----EYEGTYPLP--EALLDRFLLRIYVDypDSEEEERIILAR----VGGVDELDLESLVKPVLSDEEL <font color=#
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
<font color=# KKFIAYCRakcGPRLSAEAAEKLKNRYIIMRSGARQHERDSARRSsipitvrqlEAIVRISEALSKMKLQPFATEADV-- <font color=#
<font color=# LRLQKEVK---KVPVSDEVIDYIVTLVAALREAPDVALGASPRAS---------LALLAALRALALLDGRDAVIPDDVka <font color=#
....*....|....*....|
<font color=# --EEALRLFQVSTLDAALSG <font color=#
<font color=# laEPALAHRLILELEAKLSG <font color=#
References:
Marchler-Bauer A et al. (2015), "CDD: NCBI's conserved domain database.", Nucleic Acids Res.43(D)222-6.
Marchler-Bauer A et al. (2011), "CDD: a Conserved Domain Database for the functional annotation of proteins.", Nucleic Acids Res.39(D)225-9.
Marchler-Bauer A et al. (2009), "CDD: specific functional annotation with the Conserved Domain Database.", Nucleic Acids Res.37(D)205-10.
Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.
&of the residues that compose this conserved feature have been mapped to the query sequence.
Click on the triangle to view details about the feature, including a multiple sequence alignment
of your query sequence and the protein sequences used to curate the domain model,
where hash marks (#) above the aligned sequences show the location of the conserved feature residues.
The thumbnail image, if present, provides an approximate view of the feature's location in 3 dimensions.
Click on the triangle for interactive 3D structure viewing options.
This image shows a graphical summary of conserved domains identified on the query sequence.
The Show Concise/Full Display button at the top of the page can be used to select the desired level of detail: &only top scoring hits
() or all hits
Domains are color coded according to
to which they have been assigned.
Hits with scores that pass a domain-specific threshold
() are drawn in bright colors.
Others () and
placeholders are drawn in pastel colors.
if a domain or superfamily has been annotated with functional sites (),
they are mapped to the query sequence and indicated through sets of
with the same color and shade of the domain or superfamily that provides the annotation.
Mouse over the colored bars or triangles to see descriptions of the domains and features.
click on the bars or triangles to view your query sequence embedded in a multiple sequence alignment of the proteins used to develop the corresponding domain model.
The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores.
Click on the domain model's
to view the multiple sequence alignment of the proteins used to develop the corresponding domain model.
To view your query sequence embedded in that multiple sequence alignment, click on the colored bars in the Graphical Summary portion of the search results page,
or click on the triangles, if present, that represent functional sites ()
mapped to the query sequence.
Concise Display shows only the best scoring domain model, in each hit category listed below except non-specific hits, for each region on the query sequence.
Standard Display shows only the best scoring domain model from each source, in each hit category listed below for each region on the query sequence.
Full Display shows all domain models, in each hit category below, that meet or exceed the RPS-BLAST threshold for statistical significance.
can be shown, as available,
for each region on the query sequence:
meet or exceed a domain-specific e-value threshold
and represent a very high confidence that the query sequence belongs to the same protein family as the sequences use to create the domain model
meet or exceed the RPS-BLAST threshold for statistical significance (default E-value cutoff of 0.01, or an E-value selected by user via the
the domain
to which the specific and non-specific hits belong
models that were computationally detected and are likely to contain multiple single domains
provides more detail about the tool and its features.
Retrieve proteins that contain one or more of the domains present in the query sequence, using the Conserved Domain Architecture Retrieval Tool
Modify your query to search against a different database and/or use advanced search options