Hebei, China
ISO 9001, ISO 14000
FOB Price: US $1520.0 / Ton
Min. Order: 1 Ton
Best Quality Linear Alkylbenzene Sulphonic Acid
Product identification
Product name : Linear Alklybenzene Sulphonic Acid
Chemical synonym : LABSA
Formula : RC6H4SO3H, ...
FOB Price: $550.0 - $650.0 / Ton
Min. Order: 1 Ton
Product: Glacial Acetic Acid
Alias: G Acetic Acid Glacial BP; Natural Acetic A Acetic Acid G GAA; Acetic Acid, G Ethanoic acid
CAS No.: ...
FOB Price: $400.0 - $600.0 / Ton
Min. Order: 20 Tons
Product Description
85% Formic Acid--tanning & dyestuff chemical
1. Formic acid brief introduction:
The physicochemical properties, utilization and production of Formic ...
FOB Price: $2800.0 - $4000.0 / Mt
Min. Order: 100 g
Specifications
Chromium Trioxide, Chromic Trioxide, Chromic acid, Chromic anhydride
Brown-red flakes
Purity:99.7%min
Good quality
Product name: Chrominum Trioxide, Chromic ...
FOB Price: $180.0 - $250.0 / Ton
Min. Order: 1 Ton
Our annual capacity of hydrochloric acid(HCl) is 500, 000 mts each year. 60% for export. It is the byproduct from our other chemical program.
Name: Hydrochloric acid, HCl
FOB Price: US $50.0 / gram
Min. Order: 1 gram
ProviderLanguage
FOB Price: $1190.0 - $1320.0 / Ton
Min. Order: 1 Ton
Phosphorous acid
O Phosphonic acid
Ec no.: 233-663-1
Molecular weight: 81.996
Molecular formula: H3po3
Density: 1.6510 ...
FOB Price: $300.0 - $350.0 / FCL
Min. Order: 1 FCL
Nitric Acid
• Molecular Formula:HNO3
• CAS No. :
• HS:
• HAZARD CLASS: 8
• Purity: 68%,62%,50%,40%
• Appearance: ...
FOB Price: $2000.0 - $2100.0 / Ton
Min. Order: 10 Tons
1. Name: EDTA Acid
2. Molecular formula: C10H16N2O8
3. Molecular weight: 292.24
4. Appearance: White powder
5. Package: Packed in 25kg paper bags lined with PE bag
FOB Price: $810.0 - $1500.0 / Ton
Min. Order: 10 Tons
1. Phosphoric acid
2. Food grade. Industry grade
3. General Description: A clear colorless liquid or transparent crystalline solid. The pure solid melts at 42.35& C and has a ...
FOB Price: $550.0 - $750.0 / Ton
Min. Order: 20 Tons
Sulfamic Acid Use:
Sulfamic Acid can be used as amphoteric surfactant, metal parts cleaning agent, cyclamate sweetener, paper pulp bleacher, fire retarder, chlorine ...
FOB Price: $350.0 - $370.0 / Ton
Min. Order: 10 Tons
Quick detail:
EINECS No; 231-714-2
Molecular formula: HNO3
Molecular weight: 63.0128
Specification:
Total Acidity (as HNO3) min: 68%
Nitrous Acid ...
Product Name: Hydrobromic acid English Name: Hgdrobrmic acid
Molecular formula: HBr Molecular weight: 80.91
Physical & chemical properties: Colorless or slight yellow ...
FOB Price: $500.0 - $650.0 / Ton
Min. Order: 10 Tons
Sulfamic Acid Specification
You are buying=Our Products + Our Service
1. For whatever questions about us or our products you may have, do let us know and you can be assured ...
FOB Price: US $262.0 / Ton
Min. Order: 24 Tons
Product Description
Sulfuric Acid
Molecular formula: H2SO4
Weight: 98.08
Solubility: Compatibility with water.
UN Number: 1830
Sulphuric Acid is a ...
FOB Price: US $400.0 / Ton
Min. Order: 20 Tons
Specifications
acetic acid
industrial/ food grade/textile grade
30kgs/drum,200kgs/drum,IBC drum
good quality and best price
Acetic Acid
Molecular Formula: CH3COOH
Molecular ...
FOB Price: US $1520.0 / Ton
Min. Order: 1 Ton
Industrial Linear Alkylbenzene - LAB
Product identification
Product name : Industrial Linear Alkylbenzene
Chemical synonym : Linear Alkylbenzene
Formula : ...
High quality food grade sodium citrate powder / sodium citrate
Cidulants Sodium Citrate High Purity Acidity Regulators Sodium Citrate
Products Information:
Sodium ...
FOB Price: $230.0 - $530.0 / Ton
Min. Order: 10 Tons
Industrial hydrochloric acid manufactory
Product Name: Hydrochloric acid
Synonyms: HCl
Molecule Weight: 36.46
1. Purity: 31%
2. Direct manufacturer ...
FOB Price: $200.0 - $330.0 / Ton
Min. Order: 20 Tons
Best price---sulphuric acid
1. Export license certified
2. Competitive price
3. Fast delivery
4. Good quality
Sulfuric acid% & ...98.0
Ash& ...0.02
Fe % & ...
FOB Price: $240.0 - $290.0 / fcl
Min. Order: 1 fcl
Hydrochloric acid
• Alias: hydrogen chloride
• Molecular Formula: HCl
• CAS No. :
• HS:
• HAZARD CLASS: 8
• Purity: ...
FOB Price: US $350.0 / Ton
Min. Order: 20 Tons
General description:
Nitric acid it is an important industrial chemical for the manufacture of fertilizers, dyes, drugs, plastics, and explosives, etc.
High quality industry anticoagulant sodium citrate
Cidulants Sodium Citrate High Purity Acidity Regulators Sodium Citrate
Products Information:
High quality industry ...
Manufacturer Supply 1-Amino-8-Naphthol-3, 6-Disulfonic Acid
1.Product Description:
Product Name: 1-Amino-8-Naphthol-3, 6-Disulfonic Acid
CAS No.: 90-20-0
EINECS ...
FOB Price: $300.0 - $350.0 / Ton
Min. Order: 1 Ton
Description of Nitric Acid 68%
EINICS NO.: 231-714-2
HAZARD CLASS: 8
UN NO.: 2031
Purity: 68%
Appearce: ...
FOB Price: US $1520.0 / Ton
Min. Order: 1 Ton
96% Min High Purity LABSA for Detergent
Product identification
Product name : Linear Alklybenzene Sulphonic Acid
Chemical synonym : LABSA
Formula : RC6H4SO3H, ...
LABSA Sulfonic Acid 96% Detergent Chemicals
Characteristics
Appearance is brown sticky liquid. The product has the action of detergency, moistening, foaming, emulsion, ...
Citric Acid Monohydrate with High Quality
About Citric Acid:
1. Citric acid is a weak organic tricarboxylic acid having the chemical formula C6H8O7. It occurs naturally in ...
EDTA: Ethylene Diamine Tetraacetic Acid
Molecular formula: C10H16N2O8
Molecular weight: 292.24
Appearance: White powder
Package: Packed in 25kg paper bags lined with PE ...
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LCMS Grade Formic Acid (UltraPure)
LCMS Grade Formic Acid (UltraPure)
Package Size:
10 x 1 mL Ampules
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Package Size:
25 mL Bottle
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CovaChem's LCMS Grade Formic Acid is ideally suited as a chromatography additive for use in both HPLC and LCMS applications.
Formic acid is typically beneficial as a separations enhancer, and has a weak ion pairing effect in the mass spectrometer, making dissociation of from the analytes relatively easy, often resulting in increased ionization efficiencies, while providing the benefit of pH control to the mobile phase.
CovaChem's LCMS grade Formic acid is highly refined, and lot tested not only for purity, but also for the absence of metal ions known to be detrimental to mass spectrometer performance and ionization efficiencies.
CovaChem's LCMS Grade Formic Acid comes in two convenient package sizes (10 x 1 mL Ampules and 25 mL bottles).
The 1 mL Ampules of LCMS Grade Formic Acid are particularly useful for quickly preparing 1 Liter bottles of 0.1% Formic Acid solutions in either water or other organic solvents.
Package Sizes: 10 x 1 mL and 25 mL
Product Numbers:
or 11202-25
Product Name: LCMS Grade Formic Acid
Alternative Names: LCMS Formic A Formylic A Methanoic A Hyd Hydroxy(oxo) A O Oxocarbinic acid
Specifications
Appearance: Clear liquid
Purity: is ≥ 99%
Storage: Room Temperature
Properties
Physical State: Liquid
CAS #: 64-18-6
Chemical Formula: CH2O2
Molecular Weight: 46.03 amu
Boiling Point: 100.8 °C (Lit)
Density: 1.22 g/mL
Tariff Code: 0
Beta-Glucuronidase solution (β-Glucuronidase) is used in drug testing applications.
With our low price of 25 mL for ONLY &36;275, CovaChem is ready to become your #1 supplier of Beta-Glucuronidase.
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N,O-bis-(trimethylsilyl) acetamide (BSA) is a silylation reagent used to form stable TMS derivatives that are volatile.
BSA is used to derivatize carboxylic acids, phenols, steroids, amines, alcohols, and alkaloids.
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N,O-bis(trimethylsilyl)trifluoroacetamide (BSTFA) is a versatile silylation reagent used to form stable TMS derivatives that are volatile.
BSTFA is used to derivatize carboxylic acids, phenols, steroids, amines, alcohols, and alkaloids.
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Disuccinimidyl tartrate (DST) is an amine reactive, water soluble, cleavable crosslinker.
DST is a homobifunctional crosslinker that is reactive towards amines
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Heptaflurobutyric anhydride (HFAA) is an acylation reagent used to improve a compounds volatility and introduce fluorine atoms into an analyte compound for improved volatility.
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CovaChem's HPLC Grade Isopropanol (2-Propanol) is a high purity solvent well suited for HPLC applications, chemical synthesis and general laboratory use.
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CovaChem's LCMS Grade water is refined for optimal performance in mass spectrometry applications.
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MTBSTFA (N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide) is a silylation reagent used to rapidly silylate carboxyls, hydroxyls, primary amines, secondary amines and thiols (-SH) forming volatile derivatives easily analyzed by gas chromatography.
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anonymous customer(s)formic怎么翻译及发音
沪江词库精选formic是什么意思、英语单词推荐、用法及解释、中英文句子翻译、英语短语、英音发音音标、美音发音音标。
英音 [ 'f?:mik ] ； 美音 [ 'f?:mik ] 副词 蚁的,蚁酸的
&Formic acid (methanoic scid): Simplest carboxylic acid, chemical formula HCOOH.&
蚁酸(亦称甲酸):最简单的羧酸，化学式为HCOOH。
Of,derived from,or containing formic acid.
甲酸的甲酸的，由甲酸衍生的，含有甲酸的
A compound,such as a salt or an ester of formic acid,that contains the HCOO - radical.
甲酸盐，甲酸酯含有HCOO－的化合物，如甲酸的盐或酯等
Many other insects also produce formic as well as other kinds of acid
其他多种昆虫也能制造甲酸或其他种类的酸。
&The sticky saliva of the flicker is alkaline, perhaps to counteract the formic acid that ants secrete. &
唾液黏而呈碱性，可能用以中和蚂蚁的蚁酸。
of or relating to or derived from ants
of or containing or derived from formic acid
adv. 以前；从前
1.过去的，在前的，以前的
2.昔日的；前
3.（两者中）前者的
形成者，模型，样板
2016formic是什么意思由沪江网提供。You are using an unsupported browser. Please upgrade your browser to
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DrugBank. IdentificationNameFormic AcidAccession NumberDB01942& (EXPT01461) TypeSmall MoleculeGroupsExperimentalDescriptionFormic acid (systematically called methanoic acid) is the simplest carboxylic acid. It is an important intermediate in chemical synthesis and occurs naturally, most famously in the venom of bee and ant stings. The principal use of formic acid is as a preservative and antibacterial agent in livestock feed. [Wikipedia]StructureSynonymsAminic acidFormateFormylic acidHydrogen carboxylic acidMethanoic acidExternal Identifiers Not AvailableApproved Prescription ProductsNot AvailableApproved Generic Prescription ProductsNot AvailableApproved Over the Counter ProductsNot AvailableUnapproved/Other Products Not AvailableInternational BrandsNot AvailableBrand mixturesNameLabellerIngredientsPrenate EliteAvion Pharmaceuticals, LlcFormic AcidPrenate EssentialAvion Pharmaceuticals, LlcFormic AcidPrenate StarAvion Pharmaceuticals, LlcFormic AcidV-natalVirtus PharmaceuticalsFormic AcidSaltsName/CASStructurePropertiesNot applicableCategoriesUNIICAS number64-18-6WeightAverage: 46.0254 Monoisotopic: 46. Chemical FormulaCH2O2InChI KeyInChIKey=BDAGIHXWWSANSR-UHFFFAOYSA-NInChIInChI=1S/CH2O2/c2-1-3/h1H,(H,2,3)IUPAC Nameformic acidSMILESOC=OTaxonomyDescriptionThis compound belongs to the class of organic compounds known as carboxylic acids. These are compounds containing a carboxylic acid group with the formula -C(=O)OH.KingdomSuper ClassClassSub ClassDirect ParentAlternative Parents
SubstituentsCarboxylic acid
Hydrocarbon derivative
Organooxygen compound
Aliphatic acyclic compoundMolecular FrameworkAliphatic acyclic compoundsExternal Descriptorsmonocarboxylic acid ()Straight chain fatty acids ()Saturated fatty acids ()PharmacologyIndicationNot AvailablePharmacodynamicsNot AvailableMechanism of actionNot AvailableRelated ArticlesAbsorptionFormic acid is readily metabolized and eliminated by the body.Volume of distributionNot AvailableProtein bindingNot AvailableMetabolismNot AvailableRoute of eliminationNot AvailableHalf lifeNot AvailableClearanceNot AvailableToxicityORAL (LD50): Acute: 700 mg/kg [Mouse]. 1100 mg/kg [Rat]. 4000 mg/kg [Dog].Affected organismsNot AvailablePathwaysPathwayCategorySMPDB IDTryptophan MetabolismMetabolicAlendronate Action PathwayDrug actionZoledronate Action PathwayDrug actionWolman diseaseDiseaseAromatase deficiencyDiseaseRosuvastatin Action PathwayDrug actionFluvastatin Action PathwayDrug action17-Beta Hydroxysteroid Dehydrogenase III DeficiencyDiseaseCHILD SyndromeDiseaseSepiapterin reductase deficiencyDiseaseHyper-IgD syndromeDiseaseCerivastatin Action PathwayDrug actionPamidronate Action PathwayDrug actionAtorvastatin Action PathwayDrug actionMethotrexate Action PathwayDrug actionHyperphenylalaninemia due to dhpr-deficiencyDiseaseCholesteryl ester storage diseaseDiseaseMevalonic aciduriaDiseasePterine BiosynthesisMetabolicFolate MetabolismMetabolicAndrogen and Estrogen MetabolismMetabolicPravastatin Action PathwayDrug actionRisedronate Action PathwayDrug actionHypercholesterolemiaDiseaseSegawa syndromeDiseaseFolate malabsorption, hereditaryDiseaseSteroid BiosynthesisMetabolicIbandronate Action PathwayDrug actionSimvastatin Action PathwayDrug actionLovastatin Action PathwayDrug actionSNP Mediated EffectsNot AvailableSNP Mediated Adverse Drug ReactionsNot AvailableADMETPredicted ADMET featuresPropertyValueProbabilityHuman Intestinal Absorption+0.9726Blood Brain Barrier+0.9652Caco-2 permeable+0.6096P-glycoprotein substrateNon-substrate0.8931P-glycoprotein inhibitor INon-inhibitor0.9906P-glycoprotein inhibitor IINon-inhibitor0.9913Renal organic cation transporterNon-inhibitor0.9444CYP450 2C9 substrateNon-substrate0.8181CYP450 2D6 substrateNon-substrate0.9527CYP450 3A4 substrateNon-substrate0.8338CYP450 1A2 substrateNon-inhibitor0.9272CYP450 2C9 inhibitorNon-inhibitor0.9723CYP450 2D6 inhibitorNon-inhibitor0.9675CYP450 2C19 inhibitorNon-inhibitor0.9877CYP450 3A4 inhibitorNon-inhibitor0.9843CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.9922Ames testNon AMES toxic0.9551CarcinogenicityCarcinogens 0.6199BiodegradationReady biodegradable0.9383Rat acute toxicity1.6531 LD50, mol/kg Not applicablehERG inhibition (predictor I)Weak inhibitor0.9799hERG inhibition (predictor II)Non-inhibitor0.9886 ADMET data is predicted using , a free tool for evaluating chemical ADMET properties. () PharmacoeconomicsManufacturersNot AvailablePackagersNot AvailableDosage formsFormRouteStrengthCapsule, gelatin coatedoralTablet, coatedoralPricesNot AvailablePatentsNot AvailablePropertiesStateLiquidExperimental PropertiesSourcemelting point8.3 °CPhysPropboiling point101 °CPhysPropwater solubility1E+006 mg/L (at 25 °C)RIDDICK,JA ET AL. (1986)logP-0.54HANSCH,C ET AL. (1995)pKa3.75 (at 25 °C)RIDDICK,JA ET AL. (1986)Predicted PropertiesSourceWater Solubility477.0 mg/mLlogP-0.47logP-0.27logS1.02pKa (Strongest Acidic)4.27Physiological Charge-1Hydrogen Acceptor Count2Hydrogen Donor Count1Polar Surface Area37.3 ?2Rotatable Bond Count0Refractivity8.15 m3·mol-1Polarizability3.37 ?3Number of Rings0Bioavailability1Rule of FiveYesGhose FilterYesVeber's RuleYesMDDR-like RuleYesSpectraMass Spec (NIST) (7.52 KB) SpectraPredicted LC-MS/MSsplash10-000-092f816e62c8d2f5d56ePredicted LC-MS/MSsplash10-000-092f816e62c8d2f5d56ePredicted LC-MS/MSsplash10-000-092f816e62c8d2f5d56ePredicted LC-MS/MSsplash10-000-eb44fff7Predicted LC-MS/MSsplash10-000-eb44fff7Predicted LC-MS/MSsplash10-000-eb44fff7MSsplash10-004j--2e63b0c1e2e417b0d7471D NMRNot Available1D NMRNot Available1D NMRNot Available1D NMRNot Available2D NMRNot Available2D NMRNot AvailableReferencesSynthesis ReferenceGunter Roscher, Helmut Schaum, Heinz Schmitz, “Process for the preparation of practically formic acid-free acetic acid.” U.S. Patent US4380663, issued August, 1944.General ReferencesNot AvailableExternal LinksResourceLinkKEGG CompoundPubChem CompoundPubChem SubstanceChemSpiderChEBIPharmGKBHETDrug Product DatabaseWikipediaATC CodesNot AvailableAHFS CodesNot AvailablePDB EntriesFDA labelNot AvailableMSDS (78.4 KB) InteractionsDrug InteractionsNot AvailableFood InteractionsNot AvailableTargets1. KindProteinOrganismEscherichia coli (strain K12)Pharmacological actionunknownGeneral Function:Hydroxypyruvate isomerase activitySpecific Function:Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).Gene Name:ygbMUniprot ID:Molecular Weight: DaReferencesOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. ):993-6. [] Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. ):821-34. [] 2. KindProteinOrganismPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)Pharmacological actionunknownGeneral Function:Zinc ion bindingSpecific Function:Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).Gene Name:hemBUniprot ID:Molecular Weight:37036.6 DaReferencesOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. ):993-6. [] Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. ):821-34. [] 3. KindProteinOrganismEscherichia coli (strain K12)Pharmacological actionunknownGeneral Function:3-phosphoshikimate 1-carboxyvinyltransferase activitySpecific Function:Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.Gene Name:aroAUniprot ID:Molecular Weight:46095.29 DaReferencesOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. ):993-6. [] Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. ):821-34. [] 4. KindProteinOrganismBacillus licheniformisPharmacological actionunknownGeneral Function:Serine-type endopeptidase activitySpecific Function:Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides.Gene Name:aprUniprot ID:Molecular Weight:38907.64 DaReferencesOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. ):993-6. [] Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. ):821-34. [] 5. KindProteinOrganismHumanPharmacological actionunknownGeneral Function:S100 protein bindingSpecific Function:Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.Gene Name:FGF1Uniprot ID:Molecular Weight:17459.58 DaReferencesOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. ):993-6. [] Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. ):821-34. [] 6. KindProteinOrganismEscherichia coli (strain K12)Pharmacological actionunknownGeneral Function:Zinc ion bindingSpecific Function:Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.Gene Name:defUniprot ID:Molecular Weight:19328.23 DaReferencesOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. ):993-6. [] Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. ):821-34. [] 7. KindProteinOrganismEscherichia coli (strain K12)Pharmacological actionunknownGeneral Function:Oxo-acid-lyase activitySpecific Function:Part of a heterodimeric complex that catalyzes the two-step biosynthesis of 4-amino-4-deoxychorismate (ADC), a precursor of p-aminobenzoate (PABA) and tetrahydrofolate. In the first step, a glutamine amidotransferase (PabA) generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC. PabB, in the abse...Gene Name:pabBUniprot ID:Molecular Weight:50969.07 DaReferencesOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. ):993-6. [] Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. ):821-34. [] 8. KindProteinOrganismHumanPharmacological actionunknownGeneral Function:Zinc ion bindingSpecific Function:Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate ex...Gene Name:CA2Uniprot ID:Molecular Weight: DaReferencesOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. ):993-6. [] Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. ):821-34. [] 9. KindProteinOrganismHumanPharmacological actionunknownGeneral Function:Signal transducer activitySpecific Function:Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo a...Gene Name:HMOX1Uniprot ID:Molecular Weight: DaReferencesOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. ):993-6. [] Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. ):821-34. [] Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [] 10. KindProteinOrganismHumanPharmacological actionunknownGeneral Function:Ribonuclease a activitySpecific Function:Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA.Gene Name:RNASE1Uniprot ID:Molecular Weight: DaReferencesOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. ):993-6. [] Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. ):821-34. [] Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [] 11. KindProteinOrganismEscherichia coli (strain K12)Pharmacological actionunknownGeneral Function:Fmn bindingSpecific Function:Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.Gene Name:pyrDUniprot ID:Molecular Weight: DaReferencesOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. ):993-6. [] Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. ):821-34. [] 12. KindProteinOrganismXanthobacter autotrophicusPharmacological actionunknownGeneral Function:(s)-2-haloacid dehalogenase activitySpecific Function:Catalyzes the hydrolytic dehalogenation of small L-2-haloalkanoic acids to yield the corresponding D-2-hydroxyalkanoic acids. Active with 2-halogenated carboxylic acids and converts only the L-isomer of 2-chloropropionic acid with inversion of configuration to produce D-lactate.Gene Name:dhlBUniprot ID:Molecular Weight:27469.15 DaReferencesOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. ):993-6. [] Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. ):821-34. [] 13. KindProteinOrganismSalmonella typhimuriumPharmacological actionunknownGeneral Function:Penicillin bindingSpecific Function:This is an oxacillin-hydrolyzing beta-lactamase.Gene Name:blaUniprot ID:Molecular Weight:31685.78 DaReferencesOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. ):993-6. [] Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. ):821-34. [] 14. KindProteinOrganismProteus mirabilisPharmacological actionunknownGeneral Function:Metal ion bindingSpecific Function:Decomposes hydrogen peroxide i serves to protect cells from the toxic effects of hydrogen peroxide.Gene Name:katAUniprot ID:Molecular Weight: DaReferencesOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. ):993-6. [] Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. ):821-34. [] 15. KindProteinOrganismThermus aquaticusPharmacological actionunknownGeneral Function:Gtpase activitySpecific Function:Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.Gene Name:ffhUniprot ID:Molecular Weight: DaReferencesOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. ):993-6. [] Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. ):821-34. [] 16. KindProteinOrganismStreptomyces avidiniiPharmacological actionunknownGeneral Function:Not AvailableSpecific Function:The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).Gene Name:Not AvailableUniprot ID:Molecular Weight:18833.61 DaReferencesOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. ):993-6. [] Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. ):821-34. [] 17. KindProteinOrganismShigella flexneriPharmacological actionunknownGeneral Function:Methylglyoxal synthase activitySpecific Function:Not AvailableGene Name:mgsAUniprot ID:Molecular Weight: DaReferencesOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. ):993-6. [] Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. ):821-34. [] 18. KindProteinOrganismHumanPharmacological actionunknownGeneral Function:Transcription factor bindingSpecific Function:Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation.Gene Name:CTBP1Uniprot ID:Molecular Weight: DaReferencesOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. ):993-6. [] Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. ):821-34. [] Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [] 19. KindProteinOrganismThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Pharmacological actionunknownGeneral Function:6-phosphogluconolactonase activitySpecific Function:Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.Gene Name:pglUniprot ID:Molecular Weight: DaReferencesOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. ):993-6. [] Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. ):821-34. [] 20. KindProteinOrganismMycobacterium tuberculosisPharmacological actionunknownGeneral Function:Involved in citrate (pro-3S)-lyase activitySpecific Function:May play a role in fatty acid biosynthesis (Potential)Gene Name:citEUniprot ID:Molecular Weight:28886.0 Da21. KindProteinOrganismHumanPharmacological actionunknownGeneral Function:Protein serine/threonine kinase activitySpecific Function:Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracellular matrix and the actin ...Gene Name:CASKUniprot ID:Molecular Weight: Da22. KindProteinOrganismMycobacterium tuberculosisPharmacological actionunknownGeneral Function:Nucleotide transport and metabolismSpecific Function:Essential for recycling GMP and indirectly, cGMP (By similarity)Gene Name:gmkUniprot ID:Molecular Weight:22096.0 Da23. KindProteinOrganismThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Pharmacological actionunknownGeneral Function:Butyrate kinase activitySpecific Function:Not AvailableGene Name:buk2Uniprot ID:Molecular Weight:42022.04 Da24. KindProteinOrganismHumanPharmacological actionunknownGeneral Function:Gamma-glutamylcyclotransferase activitySpecific Function:Contributes to degradation of proteins cross-linked by transglutaminases. Degrades the cross-link between a lysine and a glutamic acid residue from two proteins that have been cross-linked by transglutaminases. Catalyzes the formation of 5-oxoproline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma-glutamyl-L-alpha-cysteine and L...Gene Name:GGACTUniprot ID:Molecular Weight:17328.44 DaReferencesBerman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [] 25. KindProteinOrganismHumanPharmacological actionunknownGeneral Function:Calcium ion bindingSpecific Function:In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.Gene Name:PVALBUniprot ID:Molecular Weight: DaReferencesBerman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [] 26. KindProteinOrganismHumanPharmacological actionunknownGeneral Function:Acylphosphatase activitySpecific Function:Its physiological role is not yet clear.Gene Name:ACYP2Uniprot ID:Molecular Weight:11139.52 DaReferencesBerman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [] 27. KindProteinOrganismBacillus cereus (strain ATCC 14579 / DSM 31)Pharmacological actionunknownGeneral Function:Not AvailableSpecific Function:Not AvailableGene Name:Not AvailableUniprot ID:Molecular Weight:12777.45 Da28. KindProteinOrganismPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)Pharmacological actionunknownGeneral Function:Arginine n-succinyltransferase activitySpecific Function:Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine. Also acts on L-ornithine.Gene Name:astAUniprot ID:Molecular Weight: Da29. KindProteinOrganismBacillus subtilis (strain 168)Pharmacological actionunknownGeneral Function:Zinc ion bindingSpecific Function:Not AvailableGene Name:yvyIUniprot ID:Molecular Weight: Da30. KindProteinOrganismHumanPharmacological actionunknownGeneral Function:Tetrahydrobiopterin bindingSpecific Function:Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.Gene Name:NOS1Uniprot ID:Molecular Weight: DaReferencesBerman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [] 31. KindProteinOrganismThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Pharmacological actionunknownGeneral Function:Metal ion bindingSpecific Function:Not AvailableGene Name:Not AvailableUniprot ID:Molecular Weight:64077.82 Da32. KindProteinOrganismEscherichia coli (strain K12)Pharmacological actionunknownGeneral Function:Zinc ion bindingSpecific Function:Hydrolyzes p-nitrophenyl phosphate (pNPP) in vitro. Involved in the swarming motility process.Gene Name:ycdXUniprot ID:Molecular Weight:26890.25 Da33. KindProteinOrganismPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)Pharmacological actionunknownGeneral Function:Isochorismatase activitySpecific Function:Not AvailableGene Name:phzD1Uniprot ID:Molecular Weight:23195.32 Da34. KindProteinOrganismBacillus subtilis (strain 168)Pharmacological actionunknownGeneral Function:Oxalate decarboxylase activitySpecific Function:Converts oxalate to formate and CO(2) in an O(2)-dependent reaction. Can also catalyze minor side reactions: oxalate oxidation to produce H(2)O(2), and oxalate-dependent, H(2)O(2)-independent dye oxidations.Gene Name:oxdCUniprot ID:Molecular Weight:43565.77 Da35. KindProteinOrganismStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)Pharmacological actionunknownGeneral Function:Oxidoreductase activitySpecific Function:Not AvailableGene Name:actIIIUniprot ID:Molecular Weight:27264.88 Da36. KindProteinOrganismHumanPharmacological actionunknownGeneral Function:Molybdopterin molybdotransferase activitySpecific Function:Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules (By similarity). Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.Gene Name:GPHNUniprot ID:Molecular Weight: DaReferencesBerman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [] 37. KindProteinOrganismBacillus cereus (strain ATCC 14579 / DSM 31)Pharmacological actionunknownGeneral Function:Not AvailableSpecific Function:Not AvailableGene Name:Not AvailableUniprot ID:Molecular Weight: Da38. KindProteinOrganismHumanPharmacological actionunknownGeneral Function:Lipid bindingSpecific Function:Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane. Involved in neurite growth (By similarity).Gene Name:CYTH2Uniprot ID:Molecular Weight: Da39. KindProteinOrganismAcidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / VR4)Pharmacological actionunknownGeneral Function:Ligase activitySpecific Function:Decarboxylase subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).Gene Name:gcdAUniprot ID:Molecular Weight:64346.32 Da40. KindProteinOrganismThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Pharmacological actionunknownGeneral Function:Dna bindingSpecific Function:Not AvailableGene Name:Not AvailableUniprot ID:Molecular Weight: Da41. KindProteinOrganismHelicobacter pylori (strain ATCC 700392 / 26695)Pharmacological actionunknownGeneral Function:Metal ion bindingSpecific Function:Decomposes hydrogen peroxide i serves to protect cells from the toxic effects of hydrogen peroxide.Gene Name:katAUniprot ID:Molecular Weight:58628.85 Da42. KindProteinOrganismThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Pharmacological actionunknownGeneral Function:Not AvailableSpecific Function:Not AvailableGene Name:Not AvailableUniprot ID:Molecular Weight: Da43. KindProteinOrganismPlasmodium falciparumPharmacological actionunknownGeneral Function:Glutathione transferase activitySpecific Function:Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May also function as a storage protein or ligandin for parasitotoxic ferriprotoporphyrin IX (hemin).Gene Name:GSTUniprot ID:Molecular Weight:24788.9 Da44. KindProteinOrganismTrypanosoma cruziPharmacological actionunknownGeneral Function:Hypoxanthine phosphoribosyltransferase activitySpecific Function:Not AvailableGene Name:HGPRTaseUniprot ID:Molecular Weight:25529.02 Da45. KindProteinOrganismBacillus subtilis (strain 168)Pharmacological actionunknownGeneral Function:Glutaminase activitySpecific Function:Not AvailableGene Name:glsA1Uniprot ID:Molecular Weight:36186.3 Da46. KindProteinOrganismEscherichia coli (strain K12)Pharmacological actionunknownGeneral Function:Glutaminase activitySpecific Function:Not AvailableGene Name:glsA1Uniprot ID:Molecular Weight: Da47. KindProteinOrganismEscherichia coli (strain K12)Pharmacological actionunknownGeneral Function:Molybdopterin synthase activitySpecific Function:Converts molybdopterin precursor Z to molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.Gene Name:moaEUniprot ID:Molecular Weight: Da48. KindProteinOrganismThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Pharmacological actionunknownGeneral Function:Transaminase activitySpecific Function:Not AvailableGene Name:Not AvailableUniprot ID:Molecular Weight:47135.19 Da49. KindProteinOrganismPasteurella haemolyticaPharmacological actionunknownGeneral Function:Metal ion bindingSpecific Function:Not AvailableGene Name:fbpAUniprot ID:Molecular Weight: Da50. KindProteinOrganismThermus thermophilusPharmacological actionunknownGeneral Function:Dna topoisomerase type ii (atp-hydrolyzing) activitySpecific Function:Not AvailableGene Name:gyrBUniprot ID:Molecular Weight: DaTransporters1. KindProteinOrganismHumanPharmacological actionunknownActionssubstrateGeneral Function:Symporter activitySpecific Function:Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).Gene Name:SLC16A3Uniprot ID:Molecular Weight:49468.9 DaReferencesManning Fox JE, Meredith D, Halestrap AP: Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle. J Physiol. 2000 Dec 1;529 Pt 2:285-93. []
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Drug created on June 13,
/ Updated on August 17,