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&&GM系列手持式数字高斯计/特斯拉计可用于测量直流磁场、 交流磁场、辐射磁场等各类磁场的磁感应强度。该仪器可以随身携带,量程范围宽,操作方便,液晶显示清晰。电源为一节9V干电池,可连续使用20小时。
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&&&&&? ? ? ? ? ? ? ? ? ? &&&&&&Text Size:人 GM2A 蛋白 (His 标签)&&|&&&&&&作者评价应用种属图像 0">Human&GM2A&蛋白产品信息分子别称:GM2-AP,SAP-3蛋白构建:A DNA sequence encoding the human GM2A (AAA35907.1) (Met 1-Ile 193) was fused with a polyhistidine tag at the C-terminus.分子种属:Human表达宿主:Baculovirus-Insect Cells运输说明:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. 0">Human&GM2A&蛋白质控检测纯度:> 96 % as determined by SDS-PAGE内毒素:< 1.0 EU per μg of the protein as determined by the LAL method稳定性:Samples are stable for up to twelve months from date of receipt at -70℃预测N端:Val 22分子量:The secreted recombinant human GM2A (pro form) comprises 180 amino acids and has a predicted molecular mass of 19.8 kDa. The apparent molecular mass of rh GM2A is approximately 25 kDa in SDS-PAGE under reducing conditions.缓冲液:Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4, 10% gly1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.2. Please
for any concerns or special requirements. 0">Human&GM2A&蛋白使用指导储存方法:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.复溶条件:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. 0">Human&GM2A&蛋白SDS-PAGEHuman GM2A Protein (His Tag) SDS-PAGEGM2A&相关信号通路Other GM2A&蛋白&Products 0">13246-H08B 0">GM2A&研究背景 GM2A (GM2 ganglioside activator), is a lipid transfer protein which belongs to the ML domain family. GM2A can accommodate several single chain phospholipids and fatty acids. It also exhibits some calcium-independent phospholipase activity. GM2A binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. GM2A acts as a substrate specific co-factor for the lysosomal enzyme &-hexosaminidase A. &-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3. Defects in GM2A are the cause of GM2-gangliosidosis type AB (GM2GAB), also known as Tay-Sachs disease AB variant. 0">Human&GM2A&参考资料
Wright CS, et al. (2003) Structural analysis of lipid complexes of GM2-activator protein. J Mol Biol. 331(4):951-64. Product nameProduct nameRelated Products
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GM2A MaxPab mouse polyclonal antibody (B02)
GM2A MaxPab mouse polyclonal antibody (B02)
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.... Frequently ....AustriaAustraliaBrazilCanadaSwitzerlandChinaCzech RepublicGermanyDenmarkSpainFinlandFranceUnited KingdomGreeceHong KongIrelandIsraelIndiaItalyJapanSouth KoreaNew ZealandPakistanSwedenSingaporeThailandTaiwanUSAVietnam... All Countries ...AfghanistanAlbaniaAlgeriaAmer.Virgin Is.AndorraAngolaAnguillaAntigua/BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBelarusBelgiumBelizeBeninBhutanBoliviaBosnia-Herz.BotswanaBrazilBrit.Virgin Is.Brunei Daruss.BulgariaBurkina FasoBurmaBurundiCambodiaCameroonCanadaCape VerdeCARCayman IslandsChadChileChinaColombiaCosta RicaCote d'IvoireCroatiaCubaCyprusCzech RepublicDem. Rep. CongoDenmarkDjiboutiDominicaDominican Rep.Dutch AntillesEast TimorEcuadorEgyptEl SalvadorEquatorial GuinEritreaEstoniaEthiopiaFalkland IslndsFijiFinlandFranceFrench GuayanaGabonGambiaGeorgiaGermanyGhanaGreeceGreenlandGrenadaGuamGuatemalaGuineaGuinea-BissauGuyanaHaitiHondurasHong KongHungaryIcelandIndiaIndonesiaIranIraqIrelandIsraelItalyJamaicaJapanJordanKazakhstanKenyaKiribatiKuwaitKyrgyzstanLaosLatviaLebanonLesothoLiberiaLibyaLiechtensteinLithuaniaLuxembourgMacauMacedoniaMalawiMalaysiaMaliMaltaMauretaniaMexicoMinor Outl.Isl.MoldovaMongoliaMontserratMoroccoMozambiqueNepalNetherlandsNew ZealandNicaraguaNigerNigeriaNorwayOmanPakistanPalauPalestinePanamaPap. New GuineaParaguayPeruPhilippinesPolandPortugalPuerto RicoQatarRep.of CongoReunionRomaniaRussian Fed.RwandaSaudi ArabiaSenegalSerbiaSierra LeoneSingaporeSlovakiaSloveniaSomaliaSouth AfricaSouth KoreaSpainSri LankaSt Kitts & NevisSt. LuciaSt. VincentSudanSurinameSwazilandSwedenSwitzerlandSyriaTaiwanTajikistanTanzaniaThailandTogoTrinidad,TobagoTunisiaTurkeyTurkmenistanUgandaUkraineUnited KingdomUruguayUSAUtd.Arab Emir.UzbekistanVenezuelaVietnamWest SaharaYemenZambiaZimbabwe
Product Description:
Mouse polyclonal antibody raised against a full-length human GM2A protein.
Immunogen:
GM2A (NP_, 1 a.a. ~ 193 a.a) full-length human protein.
MQSLMQAPLLIALGLLLAAPAQAHLKKPSQLSSFSWDNCDEGKDPAVIRSLTLEPDPIIVPGNVTLSVMGSTSVPLSSPLKVDLVLEKEVAGLWIKIPCTDYIGSCTFEHFCDVLDMLIPTGEPCPEPLRTYGLPCHCPFKEGTYSLPKSEFVVPDLELPSWLTTGNYRIESVLSSSGKRLGCIKIAASLKGI
Reactivity:
Quality Control Testing:
Antibody reactive against mammalian transfected lysate.
Storage Buffer:
No additive
Storage Instruction:
Store at -20&C or lower. Aliquot to avoid repeated freezing and thawing.
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
Datasheet:
Applications
Western Blot (Transfected lysate)
Western Blot analysis of GM2A expression in transfected 293T cell line () by GM2A MaxPab polyclonal antibody.Lane 1: GM2A transfected lysate(21.23 KDa).Lane 2: Non-transfected lysate.
Gene Pathway
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