satellitc 是什么意思_百度知道
satellitc 是什么意思
提问者采纳
有这个单词satellitesatellite
英[ˈla&#618.
卫星;sæt]
n; 卫星国;tlˌt]
美[ˈ 天然卫星;t&#601：satellites 形近词; 卫星区;
[例句]The rocket launched two commu
v; 人造卫星。[其他]
通过通讯卫星播送[传播].火箭发射了两颗通信卫星; 气象卫星;aɪs&#230
来自团队：
其他类似问题
为您推荐：
等待您来回答
下载知道APP
随时随地咨询
出门在外也不愁Manager.it
- internet dei dirigenti e quadri italianiCompound blue naevus: A potential simulator of melanoma [1] (PDF Download Available)
For full functionality of ResearchGate it is necessary to enable JavaScript.
Here are the .
See all >5 CitationsSee all >9 ReferencesSee all >1 Figure
38.86 · Hospital Clínic de Barcelona23.84 · University of Barcelona40.39 · University of BarcelonaDiscover the world's research10+ million members100+ million publications100k+ research projects
CorrespondenceCompound blue naevus: a potential simulatorof melanomaDOI: 10.1111/j.06.07287.xSIR, Blue naevus (BN) is a well-defined benign dermal melan-ocytic proliferation characterized by absence of the dermo-epidermal junctional component. It frequently shows anill-defined dermal, symmetrical, dome-shaped, and heavilypigmented lesion, with a Grenz zone, composed by a dermalproliferation of dendritic melanocytes, accompanied by avariable number of melanophages and a variable degree offibrosis.1–3In 1990, Kamino and Tam described a rare variant of BNcharacterized by the presence of an additional junctional den-dritic component, without nest formation, contiguous withthe dermal component. They coined the term ‘compound bluenaevus’.4Later, Ackerman et al.5proposed the term ‘superficialblue naevus with prominent intraepidermal dendritic melano-cytes’. To date very few papers have confirmed the existenceof this kind of BN.4–6We report an additional case of com-pound BN simulating a malignant melanoma.A 32-year-old woman presented with a 4-mm pigmentedmacule on her nipple that had recently enlarged. Clinicallythere was a black lesion that ended abruptly. A clinical diagno-sis of malignant melanoma vs. atypical pigmented Spitz naevuswas made. Histopathologically there was a symmetrical pig-mented lesion. A proliferation of solitary dendritic cells waspresent at the dermoepidermal junction and no nesting couldbe observed. Spindle-shaped and dendritic melanocytes occu-pying the papillary and upper reticular dermis, with no subepi-dermal band, were seen. Melanophages were abundantbetween fibrotic bundles (Fig. 1a,b). There were many intra-cytoplasmic melanosomes inside the epidermis and transepi-dermal elimination of melanin. No invasion of melanocytesinto the upper epidermis was present. No atypical cells ormitotic figures were seen. Immunohistochemical studies withmonoclonal antibodies, Melan-A (MART-1) and HMB-45showed that both components were of melanocytic origin,and dendritic structures were demonstrated inside the junc-tional component (Fig. 1c). A diagnosis of superficial BN withjunctional dendritic component was made. Follow-up during24 months has not shown any evidence of recurrence ormetastasis.In their original report, Kamino and Tam4described sixpatients who presented with heavily pigmented melanocyticlesions with typical features of BN within the dermis, but withan additional junctional dendritic component. They were threewomen and three men, with an average age of 31 years.Three of the lesions were located over the trunk, two on theextremities and one on the head. The diameter was between 2and 4 mm. Because of their variegated aspect and heavy pig-mentation, a clinical diagnosis of malignant melanoma wasmade in three of the six cases. After histopathological and im-munohistochemical studies benign BN was diagnosed, andduring a mean follow-up of 47 months no recurrences ormetastases were identified.Histologically all the lesions were symmetrical, well circum-scribed and dome shaped. There was a slight epidermal hyper-plasia with basal layer hyperpigmentation, and a proliferationof heavily pigmented dendritic melanocytes arranged as solit-ary units at the dermoepidermal junction, with no nest forma-tion. No invasion of melanocytes into the upper layers of theepidermis was seen. Heavily pigmented spindle-shaped anddendritic melanocytes were present within the papillary andupper reticular dermis, as solitary units and as small fasciclesbetween collagen bundles. Numerous melanophages wereassociated with the dermal melanocytes, making their evalua-tion difficult.Immunohistochemical staining demonstrated the dendriticnature of the melanocytes in both junctional and dermal com-ponents. Melanocytes presented uniform vesicular nuclei withsmall nucleoli. There was no evidence of mitoses or cytologicalatypia.In 2002, Ferrara et al. reported five further cases of this rarekind of BN, concluding that compound BN (Kamino’s naevus)is a clinically, dermoscopically and histologically distinctivevariant of BN that frequently mimics melanoma.6Three of these five cases occurred in women, and the meanage was 20AE4 years. Three lesions were localized on the trunk,one on the neck, and one on the arm. The clinical diagnosiswas BN in three cases, pigmented spindle-cell naevus in onecase, and melanoma in another case. Histological findingswere similar to those of Kamino and Tam. The only differenceobserved was a prominent pigmented parakeratosis in twocases that corresponded dermoscopically with a black lamellaor a black central blotch.Differential diagnosis in these lesions includes combinedBN, pigmented spindle-cell naevus (Reed’s naevus), malignantmelanoma, and regressed malignant melanoma.4,5The absenceof nest formation in the junctional component associated withthe characteristic features of BN in the superficial dermal com-ponent is the main clue for differential diagnosis from bothcombined BN and Reed’s naevus. The symmetry and the? 2006 British Association of Dermatologists o British Journal of Dermatology 2006 155, pp207–229 207
cytological appearance, without atypia and mitosis, are themost important features to differentiate this lesion from malig-nant BN or melanoma.2,7,8In conclusion, compound BN is a distinctive clinicopatho-logical variant of BN. It is characterized by the presence ofdendritic melanocytes along the dermoepidermal junction, aswell as within the papillary and reticular dermis. We empha-size that it is advisable to be aware of this infrequent entitybecause it may simulate malignant melanoma. Further reportsof such cases would be of great interest to determine thedermoscopic features of this variant of BN.C. CARRERAB. FERRER*J.M. MASCARO?JRJ. PALOUDepartments of Dermatology and *Pathology,Hospital Cl??nic de Barcelona,University of Barcelona, C/Villarroel 170,08036 Barcelona, SpainE-mail: criscarrer@yahoo.esReferences1 Gonza?lez-Ca?mpora R, Galera-Davidson H, Va?zquez-Ram??rez FJ, D??az-Cano S. Blue nevus: classical types and new related entities. A differ-ential diagnostic review. Pathol Res Pract 1994; 190:627–35.2 Mihm MC, Googe PB. Dermal Melanocytoses in Problematic Pigmented Lesions,a Case Method Approach. Malvern, PA: Lea & Febiger, 1990.3 Ruiter DJ, van Dijk MCRF, Ferrier CM. Current diagnostic problemsin melanoma pathology. Semin Cutan Med Surg 2003; 22:33–41.4 Kamino H, Tam ST. Compound blue nevus: a variant of blue nevuswith an additional junctional dendritic component – a clinical, histo-pathologic, and immunohistochemical study of six cases. Arch Dermatol1990; 126:1330–3.5 Ackerman AB, Cerroni L, Kerl H. Pitfalls in the Diagnosis of Malignant Mel-anoma. Philadelphia: Lea & Febiger, 1994.6 Ferrara G, Argenziano G, Zgavec B et al. ‘Compound blue nevus’: areappraisal of ‘superficial blue nevus with prominent intraepidermaldendritic melanocytes’ with emphasis on dermoscopic and histo-pathologic features. J Am Acad Dermatol 2002; 46:85–9.7 del Rio E, Va?zquez-Veiga HA, Sua?rez-Penaranda JM. Blue nevus withsatellitosis mimicking malignant melanoma. Cutis 2000; 65:301–2.8 Tran TA, Carlson JA, Basaca PC, Mihm MC. Cellular blue nevus withatypia (atypical cellular blue nevus): a clinicopathologic study ofnine cases. J Cutan Pathol 1998; 25:252–8.Conflicts of interest: none declared.Giant pilomatricoma associated withhypercalcaemia and elevated levels ofparathyroid hormone-related proteinDOI: 10.1111/j.06.07286.xSIR, We report an extraordinarily large pilomatricoma accom-panied by hypercalcaemia and increased serum levels of para-thyroid hormone (PTH)-related protein (PTH-rP).A 32-year-old Japanese man presented with a large tumouron his neck that had been growing for the past 16 years. Hecomplained of general malaise lasting several months. Thetumour had gradually enlarged and was treated by the patient,who refrained from consulting a doctor for religious reasons.Fig 1. (a) Low-power view showing a symmetrical proliferation ofpigmented melanocytes at the dermoepidermal junction and upperdermis (haematoxylin and
original magnification · 100). (b)High-power view showing the pigmented dendritic melanocytesarranged as solitary units at the dermoepidermal junction with no nestformation (haematoxylin and
original magnification · 200). (c)The dendritic nature of the junctional melanocytes is highlighted bythe immunohistochemical staining (Melan-A; original magnification· 400).? 2006 British Association of Dermatologists o British Journal of Dermatology 2006 155, pp207–229208 Correspondence
ABSTRACT: Dermal melanocytoses form a spectrum of benign intradermal melanocytic lesions composed of dendritic melanocytes, the most common of which is the blue naevus. A variety of clinical and histological appearances may be assumed, some of which can be worrisome both to the clinician and pathologist, with the most difficult differential diagnosis, in some instances, lying with malignant melanoma. This review presents and discusses the spectrum of histological appearances of this diverse group of lesions, and highlights the clinicopathological variants which are most likely to cause diagnostic difficulty. The lesions that form this spectrum and therefore will be discussed include the dermal melanocytoses such as the Mongolian spot, blue naevus and its variants, deep penetrating naevus, melanoma arising within a blue naevus and, finally, although not a member of this group, cutaneous metastatic melanoma mimicking blue naevus.Article · Jan 2008 ABSTRACT: Blue nevus is a congenital benign melanocytic tumor that classically occurs in the skin and carries low potential for malignant transformation. We report an unusual case of widely dispersed multifocal common blue nevus of the conjunctiva simulating conjunctival melanoma. A 55-year-old Hispanic woman was found to have multiple darkly pigmented lesions on her left eye. Excisional biopsy and adjuvant cryotherapy were performed. Histopathology revealed six pigmented foci within the substantia propria composed of spindle-shaped cells with a wavy dendritiform configuration consistent with common blue nevus. One lesion had associated racial melanosis and no lesion showed junctional activity or melanoma. In conclusion, conjunctival blue nevus can be multifocal and masquerade as melanoma.Article · Feb 2008 +1more author...[...]ABSTRACT: Blue nevi and related entities are a heterogenous group of congenital and acquired melanocytic tumors that includes established entities such as dendritic (&common&) blue nevus and cellular blue nevus, and their numerous clinical and pathologic variants, such as deep penetrating nevus. They share several clinical and morphologic features including their blue tinctorial properties, the presence of a dermal proliferation of spindle, fusiform or ovoid cells, associated melanin pigment (both within the melanocytic tumor cells and also within macrophages) and stromal sclerosis and, at least focal positivity for HMB-45 (Gp100). Some variants, such as deep penetrating nevus, often show considerable variation in nuclear size and shape, and, as a consequence, are at risk of being misdiagnosed as melanoma by those unfamiliar with their characteristic morphologic features. The so-called malignant blue nevus is a controversial term denoting melanomas arising in association with or exhibiting some morphologic similarities to blue nevus. There are also lesions that are probably related to blue nevi, such as the recently described pigmented epithelioid melanocytoma and the neurocristic hamartomas, whose nature, biologic behavior, and relationship to the better established entities remains to be clearly established. This review aims to present a brief overview of these lesions, highlighting their pathologic characteristics, distinguishing features and potential diagnostic pitfalls, with particular emphasis on recently described entities, molecular findings, controversial areas, and approaches to diagnosis.Article · Nov 2009 ArticleAugust 2016 · Dermatologica Sinica · Impact Factor: 0.88ArticleAugust 2016 · Korean Journal of Dermatology+2 more authors…ArticleAugust 2016 · Archives of Dermatology · Impact Factor: 4.79ArticleAugust 2016 · British Journal of Dermatology · Impact Factor: 4.28Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.This publication is classified Romeo Yellow.Last Updated: 17 Jul 16
oror log in withTusciaweb.eu - Tusciaweb.eu: il quotidiano online con tutte le notizie in tempo reale. News e ultime notizie.